The biology of the human natural killer cell

JC Roder, HF Pross - Journal of Clinical Immunology, 1982 - Springer
Natural killer (NK) cells in the human are a population of large granular lymphocytes (LGL)
with at least one unique surface antigen not expressed on cells of other lineages. NK-target …

T gamma-lymphoproliferative disease and related disorders in humans and experimental animals: a review of the clinical, cellular, and functional characteristics

CW Reynolds, KA Foon - 1984 - ashpublications.org
T gamma lymphocytes are those lymphocytes that express receptors for both the Fc portion
of IgG and sheep erythrocytes. A very high proportion of normal T gamma lymphocytes are …

Interleukin-15 triggers the proliferation and cytotoxicity of granular lymphocytes in patients with lymphoproliferative disease of granular lymphocytes

R Zambello, M Facco, L Trentin… - Blood, The Journal …, 1997 - ashpublications.org
The recently cloned cytokine interleukin-15 (IL-15) shares several functional activities with IL-
2 in different cell systems. Although IL-15 does not show sequence homology with IL-2, it …

Characterization of human granular lymphocyte subpopulations expressing HNK‐1 (Leu‐7) and Leu‐11 antigens in the blood and lymphoid tissues from fetuses …

T Abo, CA Miller, CM Balch - European journal of immunology, 1984 - Wiley Online Library
Three subpopulations of human granular lymphocytes from blood and lymphoid tissues
were characterized using combinations of the monoclonal antibodies (mAb) HNK‐1 (Leu‐7) …

Expression of natural killer cell markers in non-Hodgkin's lymphomas

CS Ng, JKC Chan, STH Lo - Human pathology, 1987 - Elsevier
One hundred forty-nine cases of non-Hodgkin's lymphoma were studied with a panel of
monoclonal antibodies, including antibodies to natural killer (NK) cells-anti-NKH1, anti-Leu …

Immunohistochemical characterization, distribution, and ultrastructure of lymphocytes bearing T-cell receptor γ/δ in inflammatory bowel disease

K Fukushima, T Masuda, H Ohtani, I Sasaki… - Gastroenterology, 1991 - Elsevier
Phenotypic characterization and distribution of γ/δ T lymphocytes in the intestinal mucosa
were investigated in ulcerative colitis and Crohn's disease by immunohistochemistry. The …

Characterization of human lymphocyte subpopulations: Alloreactive cytotoxic T-lymphocyte precursor and effector cells are phenotypically distinct from Leu 2+ …

LT Clement, MK Dagg, A Landay - Journal of clinical immunology, 1984 - Springer
Abstract The OKT8/Leu 2+ human T-cell subset contains cells which perform suppressor
and cytotoxic functions. We have recently produced two monoclonal antibodies (termed 2D2 …

The pathology of large granular lymphocyte leukemia

BA Agnarsson, TP Loughran Jr, G Starkebaum… - Human pathology, 1989 - Elsevier
The authors conducted a histopathologic study on tissues from 11 patients with the recently
described syndrome of large granular lymphocyte (LGL) leukemia. Distinctive pathologic …

Autoimmunity and B‐cell dysfunction in chronic proliferative disorders of large granular lymphocytes/natural killer cells

R Bassan, M Pronesti, M Buzzetti, P Allavena… - Cancer, 1989 - Wiley Online Library
Clinical and laboratory findings of B‐cell immune dysfunction were evaluated in ten patients
with a large granular lymphocyte/natural killer cell proliferative disease (LGL/NK‐PD) …

Malignant clonal expansion of large granular lymphocytes with a Leu-11+, Leu-7-surface phenotype: in vitro responsiveness of malignant cells to recombinant human …

S Koizumi, H Seki, T Tachinami, M Taniguchi… - 1986 - ashpublications.org
A 14-year-old Japanese female with neutropenia showed malignant proliferation of the large
granular lymphocytes (LGLs). These LGLs were E rosette+ and Fc (IgG) receptor+ and …