Satellite DNA represents one of the most fascinating parts of the repetitive fraction of the
eukaryotic genome. Since the discovery of highly repetitive tandem DNA in the 1960s, a lot …

Epigenetics is one of the most rapidly expanding fields in biology. The recent
characterization of a human DNA methylome at single nucleotide resolution, the discovery of …

Thousands of genes encoding long noncoding RNAs (lncRNAs) have been identified in all
vertebrate genomes thus far examined. The list of lncRNAs partaking in arguably important …

Long noncoding telomeric repeat-containing RNAs–TERRAs–are transcribed in a regulated
manner from telomeres throughout eukaryotes. TERRA molecules consist of chromosome …

Single-cell analysis is essential to improve our understanding of cell functionality from
cellular and subcellular aspects for diagnosis and therapy. Single-cell cultivation is one of …

China has to feed 20% of the global population with only about 5% of the planet's water
resources and 7% of its arable land. With such limited natural conditions, however, China's …

Telomeres protect chromosome ends from nucleolytic degradation, uncontrolled
recombination by DNA repair enzymes and checkpoint signaling, and they provide …

One recently identified mechanism that regulates mRNA abundance is RNA silencing, and
pioneering work in Arabidopsis thaliana and other genetic model organisms helped define …

Telomeres are heterochromatic structures at the ends of eukaryotic chromosomes. As other
heterochromatin regions, telomeres are transcribed, from the subtelomeric region towards …

Tandem DNA repeats derived from the ancestral (TTAGGG) n run were first detected at
chromosome ends of the majority of living organisms, hence the name telomeric DNA …