Clinical effectiveness and safety of montelukast in asthma. What are the conclusions from clinical trials and meta-analyses?

KLE Hon, TF Leung, AKC Leung - Drug design, development and …, 2014 - Taylor & Francis
Asthma is a common childhood atopic disease associated with chronicity and impaired
quality of life. As there is no cure for this disease, treatment relies on avoidance of triggers …

Leukotriene receptor antagonists in addition to usual care for acute asthma in adults and children

K Watts, RJPG Chavasse - Cochrane Database of Systematic …, 2012 - cochranelibrary.com
Background Acute asthma presentation in the emergency setting frequently leads to hospital
admission. Currently available treatment options include corticosteroid therapy, beta 2 …

Common pediatric respiratory emergencies

J Choi, GL Lee - Emergency Medicine Clinics, 2012 - emed.theclinics.com
Acute respiratory distress is one of the most common reasons why parents bring their
children to the emergency department (ED). Severity can range from mild, self-limiting …

Asthma in children and adolescents: a comprehensive approach to diagnosis and management

C Chang - Clinical reviews in allergy & immunology, 2012 - Springer
Asthma is a chronic disease that has a significant impact on quality of life and is particularly
important in children and adolescents, in part due to the higher incidence of allergies in …

A randomized, double-blind, placebo-controlled trial of oral montelukast in acute asthma exacerbation

ABS Zubairi, N Salahuddin, A Khawaja, S Awan… - BMC pulmonary …, 2013 - Springer
Abstract Background Leukotriene receptor antagonists (LTRAs) are well established in the
management of outpatient asthma. However, there is very little information as to their role in …

Novel therapies in asthma: leukotriene antagonists, biologic agents, and beyond

ES Papierniak, DT Lowenthal… - American journal of …, 2013 - journals.lww.com
Asthma is one of the most common conditions seen in clinical practice and carries both a
significant disease burden in terms of patient morbidity and a high economic burden in both …

Effect of addition of single dose of oral montelukast to standard treatment in acute moderate to severe asthma in children between 5 and 15 years of age: a …

VK Todi, R Lodha, SK Kabra - Archives of disease in childhood, 2010 - adc.bmj.com
Objective To study the effect of the addition of a single dose of oral montelukast to standard
therapy in acute moderate to severe asthma. Design Double-blind randomised controlled …

Can montelukast shorten prednisolone therapy in children with mild to moderate acute asthma? A randomized controlled trial

S Schuh, AR Willan, D Stephens, PT Dick… - The Journal of …, 2009 - Elsevier
OBJECTIVE: To examine whether outpatient post-stabilization therapy with montelukast
produces more treatment failures than prednisolone. STUDY DESIGN: In this randomized …

Montelukast treatment of acute asthma exacerbations in children aged 2 to 5 years: a randomized, double-blind, placebo-controlled trial

X Wang, J Zhou, X Zhao, X Yi - Pediatric Emergency Care, 2018 - journals.lww.com
Background Although montelukast has an established role in the management of chronic
asthma in children, its efficacy in acute asthma exacerbations (AAEs) in children aged 2 to 5 …

[PDF][PDF] The effect of montelukast on bronchial hyperreactivity and lung function in asthmatic children aged 6-13 years

N Visitsunthorn, V Chirdjirapong… - Asian Pacific Journal …, 2011 - apjai-journal.org
Materials and methods: This was a randomized, double-blind, placebo-controlled, crossover
study performed in 29 mild to moderate persistent asthmatic children aged 6-13 years. Each …