MicroRNAs as potential signatures of environmental exposure or effect: a systematic review

K Vrijens, V Bollati, TS Nawrot - Environmental health …, 2015 - ehp.niehs.nih.gov
Background: The exposome encompasses all life-course environmental exposures from the
prenatal period onward that influence health. MicroRNAs (miRNAs) are interesting entities …

The omniscient placenta: metabolic and epigenetic regulation of fetal programming

BM Nugent, TL Bale - Frontiers in neuroendocrinology, 2015 - Elsevier
Fetal development could be considered a sensitive period wherein exogenous insults and
changes to the maternal milieu can have long-term impacts on developmental programming …

MicroRNAs in human placental development and pregnancy complications

G Fu, J Brkić, H Hayder, C Peng - International journal of molecular …, 2013 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs, which function as critical
posttranscriptional regulators of gene expression by promoting mRNA degradation and …

Long-term metabolic risk among children born premature or small for gestational age

V Mericq, A Martinez-Aguayo, R Uauy… - Nature Reviews …, 2017 - nature.com
Accumulating evidence suggests that both the intrauterine environment and growth during
early life can influence the development of chronic noncommunicable diseases, such as …

MicroRNA-135b promotes lung cancer metastasis by regulating multiple targets in the Hippo pathway and LZTS1

CW Lin, YL Chang, YC Chang, JC Lin, CC Chen… - Nature …, 2013 - nature.com
Dysregulation of microRNAs has a critical role in cancer progression. Here we identify an
intronic microRNA, miR-135b that is upregulated in highly invasive non-small-cell lung …

miRmine: a database of human miRNA expression profiles

B Panwar, GS Omenn, Y Guan - Bioinformatics, 2017 - academic.oup.com
Motivation MicroRNAs (miRNAs) are small non-coding RNAs that are involved in post-
transcriptional regulation of gene expression. In this high-throughput sequencing era, a …

Predicting later-life outcomes of early-life exposures

K Boekelheide, B Blumberg, RE Chapin… - Environmental …, 2012 - ehp.niehs.nih.gov
Background: In utero exposure of the fetus to a stressor can lead to disease in later life.
Epigenetic mechanisms are likely mediators of later-life expression of early-life events …

Differential microRNA expression in human placentas of term intra-uterine growth restriction that regulates target genes mediating angiogenesis and amino acid …

S Thamotharan, A Chu, K Kempf, C Janzen, T Grogan… - Plos one, 2017 - journals.plos.org
Placental insufficiency leading to intrauterine growth restriction (IUGR) demonstrates
perturbed gene expression affecting placental angiogenesis and nutrient transfer from …

Small molecule, big prospects: microRNA in pregnancy and its complications

M Cai, GK Kolluru, A Ahmed - Journal of pregnancy, 2017 - Wiley Online Library
MicroRNAs are small, noncoding RNA molecules that regulate target gene expression in the
posttranscriptional level. Unlike siRNA, microRNAs are “fine‐tuners” rather than “switches” …

SARS-CoV-2 (COVID-19) as a possible risk factor for neurodevelopmental disorders

H Dubey, RK Sharma, S Krishnan… - Frontiers in …, 2022 - frontiersin.org
Pregnant women constitute one of the most vulnerable populations to be affected by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the cause of coronavirus …