The resolution of inflammation is an essential endogenous process that protects host tissues
from an exaggerated chronic inflammatory response. Multiple interactions between host …

Introduction Proresolving lipid mediators are specialized molecules (SPMs) involved in the
active resolution of the inflammatory process by regulating tissue homeostasis. The aim of …

Background Unresolved inflammation and tissue destruction are considered to underlie the
failure of dental pulp repair. As key mediators of the injury response, dental pulp stem cells …

Objectives To determine whether the combination of resolvin E1 (RvE1) and lipoxin A4
(LXA4) could promote resolution of pulpitis and to investigate the mechanism. Materials and …

Vital pulp therapy and root canal therapy (RCT) are the dominant treatment for irreversible
pulpitis. While the success rate of these procedures is favorable, they have some limitations …

Similar to the onset phase of inflammation, its resolution is a process that unfolds in a
manner that is coordinated and regulated by a panel of mediators. Lipoxin A4 (LXA4) has …

Introduction Timely resolution of pulp inflammation is a prerequisite for the healing of
inflamed dental pulp. Stromal cells, particularly fibroblasts, play a critical role in the …

Endodontics is the branch of dentistry concerned with the morphology, physiology, and
pathology of the human dental pulp and periradicular tissues. Human dental pulp is a highly …

Lipid mediators (LM) of inflammation are a class of compounds derived from ω‐3 and ω‐6
fatty acids that play a wide role in modulating inflammatory responses. Some LM possess …

Lipoxin receptor (ALX)/N-formyl peptide receptor (FPR)-2 is a G-protein–coupled receptor
that has multiple binding partners, including the endogenous lipid mediators resolvin D1 …