Single-cell sorting based on secreted products for functionally defined cell therapies

H Miwa, R Dimatteo, J de Rutte, R Ghosh… - Microsystems & …, 2022 - nature.com
Cell therapies have emerged as a promising new class of “living” therapeutics over the last
decade and have been particularly successful for treating hematological malignancies …

Scalable fabrication and use of 3D structured microparticles spatially functionalized with biomolecules

S Lee, J de Rutte, R Dimatteo, D Koo, D Di Carlo - ACS nano, 2021 - ACS Publications
Microparticles with defined shapes and spatial chemical modification can interface with cells
and tissues at the cellular scale. However, conventional methods to fabricate shaped …

[HTML][HTML] Sorting single-cell microcarriers using commercial flow cytometers

J de Rutte, R Dimatteo, S Zhu, MM Archang, D Di Carlo - SLAS technology, 2022 - Elsevier
The scale of biological discovery is driven by the vessels in which we can perform assays
and analyze results, from multi-well plates to microfluidic compartments. We report on the …

Scalable fabrication of 3D structured microparticles using induced phase separation

S Lee, J de Rutte, R Dimatteo, D Koo, D Di Carlo - bioRxiv, 2021 - biorxiv.org
Microparticles with defined shapes and spatial chemical modification can enable new
opportunities to interface with cells and tissues at the cellular scale. However, conventional …

[图书][B] Microfabrication of Three-Dimensional Complex Structures for Biomedical Applications

S Lee - 2022 - search.proquest.com
The evolution of microfabrication has greatly contributed to the advances in biology and
medicine, as it can interface with and manipulate the interactions between biological …