The T-box family of transcription factors exhibits widespread involvement throughout
development in all metazoans. T-box proteins are characterized by a DNA-binding motif …

Cellular switching from an epithelial-to-mesenchymal phenotype, and conversely from a
mesenchymal-toepithelial phenotype, are important biological programs that are operative …

The segmented body plan of vertebrates is established during somitogenesis, a well-studied
process in model organisms; however, the details of this process in humans remain largely …

Pericytes are widely believed to function as mesenchymal stem cells (MSCs), multipotent
tissue-resident progenitors with great potential for regenerative medicine. Cultured pericytes …

Zebrafish possess a unique yet poorly understood capacity for cardiac regeneration. Here,
we show that regeneration proceeds through two coordinated stages following resection of …

The origins and developmental mechanisms of coronary arteries are incompletely
understood. We show here by fate mapping, clonal analysis, and immunohistochemistry that …

Understanding the origins and roles of cardiac progenitor cells is important for elucidating
the pathogenesis of congenital and acquired heart diseases,. Moreover, manipulation of …

The mammalian heart is a highly specialized organ, comprised of many different cell types
arising from distinct embryonic progenitor populations during cardiogenesis. Three …

The proepicardial organ is an important transient structure that contributes cells to various
cardiac lineages. However, its contribution to the coronary endothelium has been disputed …

In response to the lack of a transgenic line of zebrafish labeled with heart‐specific
fluorescence in vivo to serve as a research model, we cloned a 1.6‐kb polymerase chain …