Histone deacetylase 2 selective inhibitors: a versatile therapeutic strategy as next generation drug target in cancer therapy
Acetylation and deacetylation of histone and several non-histone proteins are the two
important processes amongst the different modes of epigenetic modulation that are involved …
important processes amongst the different modes of epigenetic modulation that are involved …
In the quest for histone deacetylase inhibitors: Current trends in the application of multilayered computational methods
Histone deacetylase (HDAC) inhibitors have gained attention over the past three decades
because of their potential in the treatment of different diseases including various forms of …
because of their potential in the treatment of different diseases including various forms of …
Epigenetic drugs for mood disorders
J Peedicayil, A Kumar - Progress in Molecular Biology and Translational …, 2018 - Elsevier
There is increasing evidence that changes in epigenetic mechanisms of gene expression
are involved in the pathogenesis of mood disorders. Such evidence stems from studies …
are involved in the pathogenesis of mood disorders. Such evidence stems from studies …
A thoroughly validated virtual screening strategy for discovery of novel HDAC3 inhibitors
Histone deacetylase 3 (HDAC3) has been recently identified as a potential target for the
treatment of cancer and other diseases, such as chronic inflammation, neurodegenerative …
treatment of cancer and other diseases, such as chronic inflammation, neurodegenerative …
Epigenetic modification of phenotype in intestinal smooth muscle cells
QA Bonafiglia - 2017 - search.proquest.com
Inflammation causes proliferation of intestinal smooth muscle cells (ISMC), contributing to
the thickened intestinal wall and the dysmotility symptoms observed in inflammatory bowel …
the thickened intestinal wall and the dysmotility symptoms observed in inflammatory bowel …