Most animals reproduce sexually, but the genetic and molecular mechanisms that determine
the eventual sex of each embryo vary remarkably. DM domain genes, which are related to …

Members of the serine/arginine-rich (SR) protein family have multiple functions in the pre-
mRNA splicing reaction. In addition to being required for the removal of constitutively spliced …

In the human malaria vector Anopheles gambiae, the gene doublesex (Agdsx) encodes two
alternatively spliced transcripts, dsx-female (AgdsxF) and dsx-male (AgdsxM), that control …

Sexual reproduction is a fundamental aspect of life. It is defined by the occurrence of meiosis
and the fusion of two gametes of different sexes or mating types. Sex-determination …

Sex determination in the mosquito Aedes aegypti is governed by a dominant male-
determining factor (M factor) located within a Y chromosome–like region called the M locus …

The sterile insect technique (SIT) is an environmentally safe and proven technology to
suppress wild populations. To further advance its utility, a novel CRISPR-based technology …

In Drosophila melanogaster, the causal links among a complex behaviour, single neurons
and single genes can be demonstrated through experimental manipulations. A key player in …

One of the most striking examples of sexual dimorphism is sex-limited mimicry in butterflies,
a phenomenon in which one sex—usually the female—mimics a toxic model species …

Most metazoans occur as two sexes. Surprisingly, molecular analyses have hitherto
indicated that sex-determining mechanisms differ completely between phyla. Here we …

Haplodiploid organisms comprise about 20% of animals. Males develop from unfertilized
eggs while females are derived from fertilized eggs. The underlying mechanisms of sex …