For many decades, the inability of lesioned central neurons to regrow was accepted almost
as a" law of nature", and on the clinical level, spinal cord and brain lesions were seen as …

In addition to their well known roles within cells, purine nucleotides such as adenosine 5′
triphosphate (ATP) and guanosine 5′ triphosphate (GTP), nucleosides such as adenosine …

The capacity of CNS neurons for axonal regrowth after injury decreases as the age of the
animal at time of injury increases. After spinal cord lesions at birth, there is extensive …

In addition to their well-established roles as neurotransmitters and neuromodulators,
growing evidence suggests that nucleotides and nucleosides might also act as trophic …

Axotomy of mature rubrospinal neurons leads to a substantial atrophy of these neurons
within days after surgery. In addition, these neurons do not successfully regenerate following …

The response of the mature central nervous system (CNS) to injury differs significantly from
the response of the peripheral nervous system (PNS). Axotomized PNS neurons generally …

It was previously shown that the immediate early gene, c‐jun, was highly expressed over
long periods, in both peripheral sensory and motor neurons following axon damage or block …

Many immediate early genes are rapidly and transiently expressed in the central nervous
system following a variety of stimuli. Damage to the axons of peripheral and certain central …

The responses of the central (CNS) and peripheral (PNS) nervous system to axotomy differ
in a number of ways; these differences can be observed in both the cell body responses to …

The effect of binocular central retinal lesions on the expression of the immediate early genes
c‐fos and zif268 in the dorsal lateral geniculate nucleus (dLGN) and the visual cortex of …