Autophagy is a process that targets various intracellular elements for degradation.
Autophagy can be non-selective—associated with the indiscriminate engulfment of cytosolic …

Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …

Mitophagy is an essential mitochondrial quality control mechanism that eliminates damaged
mitochondria and the production of reactive oxygen species (ROS). The relationship …

Cellular mitophagy means that cells selectively wrap and degrade damaged mitochondria
through an autophagy mechanism, thus maintaining mitochondria and intracellular …

Mitochondria are highly dynamic organelles that participate in ATP generation and involve
calcium homeostasis, oxidative stress response, and apoptosis. Dysfunctional or damaged …

Mitophagy mediated by the recessive Parkinson's disease genes PINK1 and Parkin
responds to mitochondrial damage to preserve mitochondrial function. In the pathway …

Mitochondria are essential organelles that execute and coordinate various metabolic
processes in the cell. Mitochondrial dysfunction severely affects cell fitness and contributes …

Mitochondria play key roles in bioenergetics, metabolism, and signaling; therefore, stable
mitochondrial function is essential for cell survival, particularly in energy-intensive neuronal …

The maintenance of a healthy and functional mitochondrial network is critical during
development as well as throughout life in the response to physiological adaptations and …

Myocardial infarction is the most common form of acute coronary syndrome. Blockage of a
coronary artery due to blood clotting leads to ischemia and subsequent cell death in the form …