The bacterial spore as a mucosal vaccine delivery system

A Saggese, L Baccigalupi, G Donadio, E Ricca… - International Journal of …, 2023 - mdpi.com
The development of efficient mucosal vaccines is strongly dependent on the use of
appropriate vectors. Various biological systems or synthetic nanoparticles have been …

Mechanisms and strategies for regulating sporulation and germination of Bacillus subtilis to enhance probiotic effects

C Li, Z Liu, J Zhao, ZM Zhao - Industrial Crops and Products, 2024 - Elsevier
Bacillus subtilis microecological agents are promising feed additives to replace antibiotics in
the livestock, poultry, and aquaculture industries. B. subtilis cells can form spores that are …

Plant Growth Promotion Function of Bacillus sp. Strains Isolated from Salt-Pan Rhizosphere and Their Biocontrol Potential against Macrophomina phaseolina

S Castaldi, C Petrillo, G Donadio, FD Piaz… - International journal of …, 2021 - mdpi.com
In recent decades, intensive crop management has involved excessive use of pesticides or
fertilizers, compromising environmental integrity and public health. Accordingly, there has …

Plant Growth-Promoting Bacterial Consortia as a Strategy to Alleviate Drought Stress in Spinacia oleracea

C Petrillo, E Vitale, P Ambrosino, C Arena, R Isticato - Microorganisms, 2022 - mdpi.com
Drought stress is one of the most severe abiotic stresses affecting soil fertility and plant
health, and due to climate change, it is destined to increase even further, becoming a …

Genomic and physiological characterization of Bacilli isolated from salt-pans with plant growth promoting features

C Petrillo, S Castaldi, M Lanzilli, M Selci… - Frontiers in …, 2021 - frontiersin.org
Massive application of chemical fertilizers and pesticides has been the main strategy used to
cope with the rising crop demands in the last decades. The indiscriminate use of chemicals …

CotG Mediates spore surface permeability in Bacillus subtilis

A Saggese, G Di Gregorio Barletta, M Vittoria… - mbio, 2022 - Am Soc Microbiol
Proteins and glycoproteins that form the surface layers of the Bacillus spore assemble into
semipermeable arrays that surround and protect the spore cytoplasm. Such layers, acting …

Tetanus toxin fragment C: structure, drug discovery research and production

C Bayart, A Mularoni, N Hemmani, S Kerachni, J Jose… - Pharmaceuticals, 2022 - mdpi.com
Tetanus toxoid (TTd) plays an important role in the pharmaceutical world, especially in
vaccines. The toxoid is obtained after formaldehyde treatment of the tetanus toxin. In …

[HTML][HTML] Bacillus subtilis spores displaying RBD domain of SARS-CoV-2 spike protein

A Vetráková, RK Chovanová, R Rechtoríková… - Computational and …, 2023 - Elsevier
Bacillus subtilis spores are considered to be efficient and useful vehicles for the surface
display and delivery of heterologous proteins. In this study, we prepared recombinant spores …

[HTML][HTML] Sporulation efficiency and spore quality in a human intestinal isolate of Bacillus cereus

M Vittoria, A Saggese, GDG Barletta, S Castaldi… - Research in …, 2023 - Elsevier
Bacteria classified as Bacillus cereus sensu stricto cause two different type of
gastrointestinal diseases associated with food poisoning. Outbreaks of this opportunistic …

Spore-adsorption: Mechanism and applications of a non-recombinant display system

E Ricca, L Baccigalupi, R Isticato - Biotechnology Advances, 2021 - Elsevier
Surface display systems have been developed to express target molecules on almost all
types of biological entities from viruses to mammalian cells and on a variety of synthetic …