The tremendous increase in the bacterial resistance to the available antibiotics is a serious
problem for the treatment of various infections. Biofilm formation in bacteria significantly …

Imidazothiazole derivatives are becoming increasingly important in therapeutic use due to
their outstanding physiological activities. Recently, applying imidazothiazole as the core …

Aim Herein, the anti-parasitic activity of azoles (fluconazole and itraconazole) and 5-
nitroimdazole (metronidazole) against the brain-eating amoebae: Naegleria fowleri and …

Background In vitro models for studying interactions between Acanthamoeba and host cells
are crucial for understanding the pathomechanism of Acanthamoeba and assessing …

Neglected tropical diseases (NTDs) comprise a diverse set of infections with predominant
incidence in tropical and sub-tropical areas of the world. In spite of preventive and …

Acanthamoeba castellanii is an opportunistic pathogen with public health implications,
largely due to its invasive nature and non-specific symptoms. Our study focuses on the …

Naegleria fowleri (N. fowleri) is a free-living, unicellular, opportunistic protist responsible for
the fatal central nervous system infection, primary amoebic meningoencephalitis (PAM) …