Pyrrole: An Essential Framework in the Development of Therapeutic Agents and Insightful Analysis of Structure‐Active Relationships

B Sahu, R Sahu, B Gidwani, A Mishra - ChemistrySelect, 2024 - Wiley Online Library
Pyrrole is a heterocyclic structure with diverse pharmacophores, enabling the creation of an
extensive lead molecule library. Its broad range of pharmacological profiles has concerned …

Efficient synthesis of aza-arenes with multiple basic sites enhanced by protonation process

F Wang, Y Bai, E Berdimurodov, T Zhang, R Bai, M Li… - Molecular …, 2024 - Elsevier
The acid-catalyzed synthesis of aza-arenes with multiple basic sites (Ar (N) NR 2) frequently
encountered an intrinsic problem caused by a poison effect of the basic substrate on the …

3D-QSAR, ADMET, and molecular docking studies of aztreonam analogs as E. colis inhibitors

ML Mitku, W Simegn, GS Chanie… - SAGE Open …, 2024 - journals.sagepub.com
Background: The development of multidrug resistant strains of extended-spectrum β-
lactamase-producing Escherichia coli has become a global problem; therefore, the …

[PDF][PDF] In silico prediction of physicochemical properties and drug-likeness of omega-3 fatty acids

Y STANEVA, I ILIEV, S GEORGIEVA, A MERDJANOVA - 2024 - sciendo.com
Omega-3 fatty acids, including alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and
docosahexaenoic acid (DHA), are recognized for their crucial roles in human health …