The comet assay is a versatile method to detect nuclear DNA damage in individual
eukaryotic cells, from yeast to human. The types of damage detected encompass DNA …

The comet assay (single cell gel electrophoresis) is the most common method for measuring
DNA damage in eukaryotic cells or disaggregated tissues. The assay depends on the …

BlueScreen HC is a mammalian cell-based assay for measuring the genotoxicity and
cytotoxicity of chemical compounds and mixtures. The BlueScreen HC assay has been …

The comet assay (single-cell gel electrophoresis) is a simple method for measuring
deoxyribonucleic acid (DNA) strand breaks in eukaryotic cells. Cells embedded in agarose …

We present a procedure for the comet assay, a gel electrophoresis–based method that can
be used to measure DNA damage in individual eukaryotic cells. It is versatile, relatively …

Betalains are unique nitrogen-containing pigments found exclusively in families of the
Caryophyllales order and some higher order fungi, where they replace anthocyanin …

Physical, chemical and biological agents can act in the DNA, resulting in mutation involved
in cancer. Thus, genotoxic tests are required by regulatory agencies in order to evaluate …

Abstract The Scientific Committee reviewed the current state‐of‐the‐science on genotoxicity
testing and provided a commentary and recommendations on genotoxicity testing strategies …

BACKGROUND Diabetes mellitus (DM) is increasing in men of reproductive age. Despite
this, the prevalence of diabetes in men attending fertility clinics is largely unknown …

The free radical theory of aging hypothesizes that oxygen-derived free radicals are
responsible for the age-related damage at the cellular and tissue levels. In a normal …