It is now established that airway smooth muscle (ASM) has roles in determining airway
structure and function, well beyond that as the major contractile element. Indeed, changes in …

Airway structure and function are key aspects of normal lung development, growth, and
aging, as well as of lung responses to the environment and the pathophysiology of important …

Airway hyperresponsiveness and inflammation are fundamental hallmarks of allergic
asthma that are accompanied by increases in certain polycations, such as eosinophil …

Atherosclerosis is one of the most important problems in modern medicine. Its high
prevalence and social significance determine the need for a better understanding of the …

The aim of the present study was to investigate mechanism of the gender differences of B
cells. The results showed that 358 differential gene expressions (DEGs) were displayed …

Epidemiological data suggests increased prevalence of asthma in females than males,
suggesting a plausible role for sex-steroids, especially estrogen in the lungs. Estrogen …

Propofol, one of the most commonly used intravenous anesthetic agents, has been reported
to have anti-inflammatory property. However, the anti-allergic inflammation effect of propofol …

Aims Obstructive sleep apnea (OSA) is a risk factor for steroid-resistant (SR) asthma.
However, the underlying mechanism is not well defined. This study aimed to investigate how …

Long‐term exposure to cigarette smoke (CS) triggers airway hyperreactivity and remodeling,
effects that involve airway smooth muscle (ASM). We previously showed that CS …

Vascular smooth muscle cells (vSMCs) retain the ability to undergo modulation in their
phenotypic continuum, ranging from a mature contractile state to a proliferative, secretory …