Obesity is accompanied by a systemic chronic low-grade inflammation as well as
dysfunctions of several innate and adaptive immune cells. Recent findings emphasize an …

Natural killer (NK) cells play a significant role in immune tolerance and immune surveillance.
Killer immunoglobin-like receptors (KIRs), which recognize human leukocyte antigen (HLA) …

In recent studies, NKG2A is revealed to be a key immune checkpoint for both natural killer
(NK) cells and CD8+ T cells. It form heterodimer receptors with CD94, and targets the …

Ovarian cancer (OC) is diagnosed in~ 22,000 women in the US each year and kills 14,000
of them. Often, patients are not diagnosed until the later stages of disease, when treatment …

Hematopoietic stem cell transplantation from a haploidentical donor is increasingly used
and has become a standard donor option for patients lacking an appropriately matched …

Periodontal diseases, ranging from gingivitis to periodontitis, are prevalent oral diseases
affecting over 50% of the global population. These diseases arise from infections and …

Objectives: The mechanism and immunoregulatory role of human natural killer (NK) cells in
acute graft-vs.-host-disease (aGVHD) remains unclear. This study quantitatively analyzed …

Hematopoietic cell transplantation (HCT) represents a potentially curative therapeutic
approach for various hematologic and non-hematologic malignancies. Human leukocyte …

Natural killer (NK) cells are one of the innate immune cells that play an important role in
preventing and controlling tumors and viral diseases, but their role in hematopoietic stem …

In the context of allogeneic transplant platforms, human leukocyte antigen (HLA)-
haploidentical hematopoietic stem cell transplantation (haplo-HSCT) represents one of the …