Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces
severe neural injuries, and is one of the leading causes of death and disability worldwide …

Microglia are emerging as critical regulators of neuronal function and behavior in nearly
every area of neuroscience. Initial reports focused on classical immune functions of …

There is growing evidence that excessive microglial phagocytosis of neurons and synapses
contributes to multiple brain pathologies. RNA‐seq and genome‐wide association (GWAS) …

Background Cerebral ischemia–reperfusion (I/R) injury is a major cause of early
complications and unfavorable outcomes after endovascular thrombectomy (EVT) therapy in …

Aims Phagocytosis is the cellular digestion of extracellular particles, such as pathogens and
dying cells, and is a key element in the evolution of central nervous system (CNS) disorders …

Ischemic stroke (IS) is one of the major types of cerebrovascular diseases causing
neurological morbidity and mortality worldwide. In the pathophysiological process of IS …

Microglia are the resident immune cells of the central nervous system that exert diverse roles
in the pathogenesis of ischemic stroke. During the past decades, microglial polarization and …

Stroke, including ischemic stroke and hemorrhagic stroke can cause massive neuronal
death and disruption of brain structure, which is followed by secondary inflammatory injury …

After stroke, there is a rapid necrosis of all cells in the infarct, followed by a delayed loss of
neurons both in brain areas surrounding the infarct, known as 'selective neuronal loss', and …

A phenomenon known for over 100 years named “cell-in-cell”(CIC) is now undergoing its
renaissance, mostly due to modern cell visualization techniques. It is no longer an esoteric …