Matrix metalloproteinase processing of signaling molecules to regulate inflammation

GS Butler, CM Overall - Periodontology 2000, 2013 - Wiley Online Library
Inflammation is a complex and highly regulated process that facilitates the clearance of
pathogens and mediates tissue repair. Failure to resolve inflammation can lead to chronic …

Recent progress in predicting protein sub-subcellular locations

P Du, T Li, X Wang - Expert Review of Proteomics, 2011 - Taylor & Francis
In the last two decades, the number of the known protein sequences increased very rapidly.
However, a knowledge of protein function only exists for a small portion of these sequences …

GOASVM: a subcellular location predictor by incorporating term-frequency gene ontology into the general form of Chou's pseudo-amino acid composition

S Wan, MW Mak, SY Kung - Journal of theoretical biology, 2013 - Elsevier
Prediction of protein subcellular localization is an important yet challenging problem.
Recently, several computational methods based on Gene Ontology (GO) have been …

Predicting plant protein subcellular multi-localization by Chou's PseAAC formulation based multi-label homolog knowledge transfer learning

S Mei - Journal of theoretical biology, 2012 - Elsevier
Recent years have witnessed much progress in computational modeling for protein
subcellular localization. However, there are far few computational models for predicting …

Predicting peroxidase subcellular location by hybridizing different descriptors of Chou'pseudo amino acid patterns

YC Zuo, Y Peng, L Liu, W Chen, L Yang, GL Fan - Analytical biochemistry, 2014 - Elsevier
Peroxidases as universal enzymes are essential for the regulation of reactive oxygen
species levels and play major roles in both disease prevention and human pathologies …

Identify Golgi protein types with modified mahalanobis discriminant algorithm and pseudo amino acid composition

H Ding, L Liu, FB Guo, J Huang… - Protein and peptide …, 2011 - ingentaconnect.com
The Golgi apparatus is an important eukaryotic organelle. Successful prediction of Golgi
protein types can provide valuable information for elucidating protein functions involved in …

Multi-kernel transfer learning based on Chou's PseAAC formulation for protein submitochondria localization

S Mei - Journal of Theoretical Biology, 2012 - Elsevier
Protein sub-organelle localization, eg submitochondria, seems more challenging than
general protein subcellular localization, because the determination of protein's micro-level …

Using over-represented tetrapeptides to predict protein submitochondria locations

H Lin, W Chen, LF Yuan, ZQ Li, H Ding - Acta biotheoretica, 2013 - Springer
The mitochondrion is a key organelle of eukaryotic cell that provides the energy for cellular
activities. Correctly identifying submitochondria locations of proteins can provide plentiful …

Gene ontology based transfer learning for protein subcellular localization

S Mei, W Fei, S Zhou - BMC bioinformatics, 2011 - Springer
Background Prediction of protein subcellular localization generally involves many complex
factors, and using only one or two aspects of data information may not tell the true story. For …

An ensemble classifier for eukaryotic protein subcellular location prediction using gene ontology categories and amino acid hydrophobicity

L Li, Y Zhang, L Zou, C Li, B Yu, X Zheng, Y Zhou - PLoS One, 2012 - journals.plos.org
With the rapid increase of protein sequences in the post-genomic age, it is challenging to
develop accurate and automated methods for reliably and quickly predicting their …