Blood flow and muscle metabolism: a focus on insulin action
MG Clark, MG Wallis, EJ Barrett… - American Journal …, 2003 - journals.physiology.org
The vascular system controls the delivery of nutrients and hormones to muscle, and a
number of hormones may act to regulate muscle metabolism and contractile performance by …
number of hormones may act to regulate muscle metabolism and contractile performance by …
Insulin action and insulin resistance: diseases involving defects in insulin receptors, signal transduction, and the glucose transport effector system 1
SJ Hunter, WT Garvey - The American journal of medicine, 1998 - amjmed.com
The concept of insulin resistance arose with the availability of insulin therapy for diabetes
mellitus. It soon became evident that diabetic patients could be divided into two groups …
mellitus. It soon became evident that diabetic patients could be divided into two groups …
Estimated glucose disposal rate for predicting cardiovascular events and mortality in patients with non-diabetic chronic kidney disease: a prospective cohort study
J Peng, Y Zhang, Y Zhu, W Chen, L Chen, F Ma, B Yi… - BMC medicine, 2024 - Springer
Background Evidence suggests that insulin resistance (IR) is an autonomous risk factor for
cardiovascular disease (CVD). Nevertheless, the association between estimated glucose …
cardiovascular disease (CVD). Nevertheless, the association between estimated glucose …
Skeletal muscle blood flow. A possible link between insulin resistance and blood pressure.
AD Baron, G Brechtel-Hook, A Johnson, D Hardin - Hypertension, 1993 - Am Heart Assoc
Insulin resistance has recently been found to be a common feature of essential
hypertension. We have tested the hypothesis that reduced skeletal muscle blood flow in …
hypertension. We have tested the hypothesis that reduced skeletal muscle blood flow in …
Abnormal sympathetic overactivity evoked by insulin in the skeletal muscle of patients with essential hypertension.
The reason why hyperinsulinemia is associated with essential hypertension is not known. To
test the hypothesis of a pathophysiologic link mediated by the sympathetic nervous system …
test the hypothesis of a pathophysiologic link mediated by the sympathetic nervous system …
Hemodynamic actions of insulin in rat skeletal muscle: evidence for capillary recruitment
S Rattigan, MG Clark, EJ Barrett - Diabetes, 1997 - Am Diabetes Assoc
Insulin-induced increases in blood flow are hypothesized to enhance overall glucose uptake
by skeletal muscle. Whether the insulin-mediated changes in blood flow are associated with …
by skeletal muscle. Whether the insulin-mediated changes in blood flow are associated with …
Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow
MA Vincent, D Dawson, ADH Clark, JR Lindner… - Diabetes, 2002 - Am Diabetes Assoc
Supraphysiological doses of insulin enhance total limb blood flow and recruit capillaries in
skeletal muscle. Whether these processes change in response to physiological …
skeletal muscle. Whether these processes change in response to physiological …
Insulin resistance and hypertension: the Insulin Resistance Atherosclerosis study
The association between insulin resistance and insulinemia and hypertension is
controversial. We examined the relation between insulin resistance and hypertension in 564 …
controversial. We examined the relation between insulin resistance and hypertension in 564 …
Insulin as a vascular hormone: implications for the pathophysiology of cardiovascular disease
1. Metabolic disorders, such as obesity and non‐insulin‐dependent diabetes mellitus, and
cardiovascular disorders, such as essential hypertension, congestive cardiac failure and …
cardiovascular disorders, such as essential hypertension, congestive cardiac failure and …
Insulin-mediated vasodilation: impairment with increased blood pressure and body mass
RD Feldman, GS Bierbrier - The Lancet, 1993 - Elsevier
Insulin resistance is associated with hypertension although it is not known if this relationship
is casual. Studies have shown that insulin increases skeletal-muscle blood flow despite also …
is casual. Studies have shown that insulin increases skeletal-muscle blood flow despite also …