Cell survival and death are intricately governed by apoptosis, a meticulously controlled
programmed cell death. Apoptosis is vital in facilitating embryonic development and …

In this elucidation, the novel thaizolone derivatives 8a-n were synthesised via the reaction
between thioamide derivatives 4a, b with chloroacetic acid and the appropriate aldehyde …

Chemotherapy is an important treatment modality for gastric cancer, and multidrug
resistance (MDR) represents a major obstacle for successful cancer chemotherapy. There is …

Background Cancer, one of the leading causes of death worldwide, develops when the
normal balance between mitosis and apoptosis is disrupted. The subsequently increased …

Recent advancements in gene delivery systems that specifically target a variety of cancer
types have increased demand for tissue-specific gene therapy. The current study describes …

Chemotherapy is a vital option for cancer treatment; however, its therapeutic outcomes are
limited by dose-dependent toxicity and the occurrence of chemoresistance. siRNAs have …

Aims High-Density Lipoprotein (HDL) is a complex structure unique to the human body.
ApoA-1 protein is a significant structural/functional protein of HDL and provides a natural …

Tumorigenesis is related to an imbalance in controlling mechanisms of apoptosis.
Expression of the genes BCL-2 and BCL-xL results in the promotion of cell survival by …

Uterine smooth muscle tumors are the most common female genital tract neoplasms. While
leiomyosarcoma has been studied at length, smooth muscle tumors of uncertain malignant …

A pH sensitive micellar cargo was fabricated for pH triggered delivery of hydrophobic drug
paclitaxel with pH controlled drug release profiles. The size, drug loading content, and …