Much of what we know regarding bacterial spore structure and function has been learned
from studies of the genetically well-characterized bacterium Bacillus subtilis. Molecular …

Bacillus anthracis has been identified as a potential military and bioterror agent as it is
relatively simple to produce, with spores that are highly resilient to degradation in the …

Blood coagulation often accompanies bacterial infections and sepsis and is generally
accepted as a consequence of immune responses. Though many bacterial species can …

Anthrax is a lethal disease caused by the bacterium Bacillus anthracis. There are three
principal forms of the disease in humans—cutaneous, gastrointestinal, and inhalational …

Anthrax is rare among humans, few data can be collected from infected individuals and they
provide a fragmentary view of the dynamics of infection and human host–pathogen …

Bacillus anthracis lethal toxin (LT) is a determinant of lethal anthrax. Its function in myeloid
cells is required for bacterial dissemination, and LT itself can directly trigger dysfunction of …

The conservative nature of animal evolution makes animal models the ideal tool for learning
about human biology. The Handbook of Laboratory Animal Science, Second Edition: Animal …

Subunit vaccines against anthrax based on recombinant protective antigen (PA) potentially
offer more consistent and less reactogenic anthrax vaccines but require adjuvants to …

Spores of Bacillus anthracis, the causative agent of anthrax, are known to persist in the host
lungs for prolonged periods of time, however the underlying mechanism is poorly …

We sought to visualize the site of Bacillus anthracis spore germination in vivo. For that
purpose, we constructed a reporter plasmid with the lux operon under control of the spore …