Neutrophils in acute inflammation: current concepts and translational implications

A Margraf, CA Lowell, A Zarbock - Blood, The Journal of the …, 2022 - ashpublications.org
Modulation of neutrophil recruitment and function is crucial for targeting inflammatory cells to
sites of infection to combat invading pathogens while, at the same time, limiting host tissue …

Mammalian glycosylation in immunity

JD Marth, PK Grewal - Nature Reviews Immunology, 2008 - nature.com
Glycosylation produces a diverse and abundant repertoire of glycans, which are collectively
known as the glycome. Glycans are one of the four fundamental macromolecular …

Recapitulation of IVIG anti-inflammatory activity with a recombinant IgG Fc

RM Anthony, F Nimmerjahn, DJ Ashline, VN Reinhold… - Science, 2008 - science.org
It is well established that high doses of monomeric immunoglobulin G (IgG) purified from
pooled human plasma [intravenous immunoglobulin (IVIG)] confer anti-inflammatory activity …

VEGF expression by mesenchymal stem cells contributes to angiogenesis in pancreatic carcinoma

BM Beckermann, G Kallifatidis, A Groth… - British journal of …, 2008 - nature.com
Little is known about the factors that enable the mobilisation of human mesenchymal stem
cells (MSC) from the bone marrow into the blood stream and their recruitment to and …

Glycosylation in immune cell trafficking

M Sperandio, CA Gleissner, K Ley - Immunological reviews, 2009 - Wiley Online Library
Leukocyte recruitment encompasses cell adhesion and activation steps that enable
circulating leukocytes to roll, arrest, and firmly adhere on the endothelial surface before they …

Myeloperoxidase attracts neutrophils by physical forces

A Klinke, C Nussbaum, L Kubala… - Blood, The Journal …, 2011 - ashpublications.org
Recruitment of polymorphonuclear neutrophils (PMNs) remains a paramount prerequisite in
innate immune defense and a critical cofounder in inflammatory vascular disease …

PSGL‐1 function in immunity and steady state homeostasis

DA Carlow, K Gossens, S Naus… - Immunological …, 2009 - Wiley Online Library
The substantial importance of P‐selectin glycoprotein ligand 1 (PSGL‐1) in leukocyte
trafficking has continued to emerge beyond its initial identification as a selectin ligand. PSGL …

The cancer glycome: carbohydrates as mediators of metastasis

SV Glavey, D Huynh, MR Reagan, S Manier… - Blood reviews, 2015 - Elsevier
Glycosylation is a frequent post-translational modification which results in the addition of
carbohydrate determinants,“glycans”, to cell surface proteins and lipids. These glycan …

Expression of ST3GAL4 Leads to SLex Expression and Induces c-Met Activation and an Invasive Phenotype in Gastric Carcinoma Cells

C Gomes, H Osorio, MT Pinto, D Campos, MJ Oliveira… - PloS one, 2013 - journals.plos.org
Sialyl-Lewis X (SLex) is a sialylated glycan antigen expressed on the cell surface during
malignant cell transformation and is associated with cancer progression and poor prognosis …

RAGE and ICAM-1 cooperate in mediating leukocyte recruitment during acute inflammation in vivo

D Frommhold, A Kamphues, I Hepper… - Blood, The Journal …, 2010 - ashpublications.org
The receptor for advanced glycation end products (RAGE) contributes to the inflammatory
response in many acute and chronic diseases. In this context, RAGE has been identified as …