Glycosylation produces a diverse and abundant repertoire of glycans, which are collectively known as the glycome. Glycans are one of the four fundamental macromolecular …
It is well established that high doses of monomeric immunoglobulin G (IgG) purified from pooled human plasma [intravenous immunoglobulin (IVIG)] confer anti-inflammatory activity …
BM Beckermann, G Kallifatidis, A Groth… - British journal of …, 2008 - nature.com
Little is known about the factors that enable the mobilisation of human mesenchymal stem cells (MSC) from the bone marrow into the blood stream and their recruitment to and …
M Sperandio, CA Gleissner, K Ley - Immunological reviews, 2009 - Wiley Online Library
Leukocyte recruitment encompasses cell adhesion and activation steps that enable circulating leukocytes to roll, arrest, and firmly adhere on the endothelial surface before they …
A Klinke, C Nussbaum, L Kubala… - Blood, The Journal …, 2011 - ashpublications.org
Recruitment of polymorphonuclear neutrophils (PMNs) remains a paramount prerequisite in innate immune defense and a critical cofounder in inflammatory vascular disease …
DA Carlow, K Gossens, S Naus… - Immunological …, 2009 - Wiley Online Library
The substantial importance of P‐selectin glycoprotein ligand 1 (PSGL‐1) in leukocyte trafficking has continued to emerge beyond its initial identification as a selectin ligand. PSGL …
Glycosylation is a frequent post-translational modification which results in the addition of carbohydrate determinants,“glycans”, to cell surface proteins and lipids. These glycan …
C Gomes, H Osorio, MT Pinto, D Campos, MJ Oliveira… - PloS one, 2013 - journals.plos.org
Sialyl-Lewis X (SLex) is a sialylated glycan antigen expressed on the cell surface during malignant cell transformation and is associated with cancer progression and poor prognosis …
D Frommhold, A Kamphues, I Hepper… - Blood, The Journal …, 2010 - ashpublications.org
The receptor for advanced glycation end products (RAGE) contributes to the inflammatory response in many acute and chronic diseases. In this context, RAGE has been identified as …