Importance Blood-based biomarkers associated with increased risk of Alzheimer disease
(AD) are understudied in people living with and without HIV, particularly women. Objective …

To explore genome organization and function in the HIV-infected brain, we applied single-
nuclei transcriptomics, cell-type-specific chromosomal conformation mapping, and viral …

HIV infection is a multi-organ disease that involves the central nervous system (CNS). While
devastating CNS complications such as HIV-associated dementia and CNS opportunistic …

Combination antiretroviral treatment (cART) has revolutionized the management of human
immunodeficiency virus (HIV) and has markedly improved the disease burden and life …

Background Primary human immunodeficiency virus (HIV) is characterized by dynamic
changes in viral load and innate and adaptive immune responses; it is unclear the extent to …

The central nervous system (CNS) is a major human immunodeficiency virus type-1 (HIV-1)
reservoir. Microglia are the primary target cell of HIV-1 infection in the CNS. Current models …

This study examined the interactive effects of early life stress (ELS) and HIV on brain
morphometry, diffusion-basis-spectrum-imaging (DBSI), risky decision-making, and sex-risk …

Background: Primary HIV is characterized by dynamic changes in viral load and innate and
adaptive immune responses; it is unclear the extent to which time from acquisition to ART …