Liquid biopsies, in particular, analysis of cell-free DNA (cfDNA), have emerged as a
promising noninvasive diagnostic approach in oncology. Abnormal distribution of DNA …

Carcinogenesis is accompanied by widespread DNA methylation changes within the cell.
These changes are characterized by a globally hypomethylated genome with focal …

DNA methylation is an epigenetic mechanism regulating gene expression. Changes in DNA
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …

New non-invasive approaches that can complement and improve on current strategies for
colorectal cancer (CRC) screening and management are urgently needed. A growing …

Lung, breast, colorectal, and prostate cancers are the most incident worldwide. Optimal
population-based cancer screening methods remain an unmet need, since cancer detection …

The increase in recent scientific studies on cancer biomarkers has brought great new
insights into the field. Moreover, novel technological breakthroughs such as long read …

The purpose of this systematic review was to compare the diagnostic ability of blood markers
for colorectal cancer (CRC). A systematic review of the literature for diagnostic blood …

Background: Colorectal cancer (CRC) follows a protracted stepwise progression, from
benign adenomas to malignant adenocarcinomas. If detected early, 90% of deaths are …

Colorectal cancer (CRC) is one of the most prevalent malignancies affecting the
gastrointestinal tract and is ranked third among cancers with the highest incidence and …

Colorectal cancer (CRC) is the second leading cause of cancer death worldwide that is
attributed to gradual long‐term accumulation of both genetic and epigenetic changes. To …