Heart transplantation (HT) remains the preferred therapy for patients with advanced heart
failure. However, for sensitized HT candidates who have antibodies to human leukocyte …

Implementation of the kidney allocation system in 2014 greatly reduced access disparity due
to human leukocyte antigen (HLA) sensitization. To address persistent disparity related to …

Highlights• HLA sensitization in heart transplant candidates is increasingly common due to
use of mechanical circulatory support and transplantation of candidates with adult …

The largely one-size-fits-all kidney allocation system is in desperate need of an overhaul.
The continuous distribution paradigm is flexible enough to accommodate bold, new ideas for …

On 24 January 2023, Eurotransplant has introduced the virtual crossmatch for kidney and
pancreas allocation as a better alternative for the physical Complement Dependent …

Background. Homozygosity for HLAs has been associated with adverse outcomes after viral
infection as well as pregnancy-induced HLA sensitization. We sought to assess the …

Calculated panel reactive antibody (CPRA) is used to help increase sensitized patient's
access to transplantation. United Arab Emirates (UAE) has a diverse resident population …

Background At the start of 2020, the kidney waiting list consisted of 2526 candidates with a
calculated panel reactive antibody (CPRA) of 99.9% or greater, a cohort demonstrated in …

Recent studies showed that ABO‐adjusted calculated panel reactive antibody (ABO‐cPRA)
may better reflect the histocompatibility level in a multi‐ethnic population, but such data in …

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