[HTML][HTML] Review of hybrid PLGA nanoparticles: Future of smart drug delivery and theranostics medicine

J Ghitman, EI Biru, R Stan, H Iovu - Materials & Design, 2020 - Elsevier
The concept of PLGA-lipid hybrid nanoparticles arose as a motivation for developing drug
delivery systems with versatile physical and chemical properties, unequivocal therapeutic …

Pancreatic cancer chemoresistance to gemcitabine

M Amrutkar, IP Gladhaug - Cancers, 2017 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC), commonly referred to as pancreatic cancer,
ranks among the leading causes of cancer-related deaths in the Western world due to …

Lipid-based drug delivery systems in cancer therapy: what is available and what is yet to come

P Yingchoncharoen, DS Kalinowski… - Pharmacological …, 2016 - ASPET
Cancer is a leading cause of death in many countries around the world. However, the
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …

Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology

N Bertrand, J Wu, X Xu, N Kamaly… - Advanced drug delivery …, 2014 - Elsevier
Cancer nanotherapeutics are progressing at a steady rate; research and development in the
field has experienced an exponential growth since early 2000's. The path to the …

Recent advances of cocktail chemotherapy by combination drug delivery systems

Q Hu, W Sun, C Wang, Z Gu - Advanced drug delivery reviews, 2016 - Elsevier
Combination chemotherapy is widely exploited for enhanced cancer treatment in the clinic.
However, the traditional cocktail administration of combination regimens often suffers from …

Cell membrane-camouflaged nanoparticles for drug delivery

BT Luk, L Zhang - Journal of Controlled Release, 2015 - Elsevier
Nanoparticles can preferentially accumulate at sites of action and hold great promise to
improve the therapeutic index of many drugs. While conventional methods of nanocarrier …

Triple conjugated carbon dots as a nano-drug delivery model for glioblastoma brain tumors

SD Hettiarachchi, RM Graham, KJ Mintz, Y Zhou… - Nanoscale, 2019 - pubs.rsc.org
Most of the dual nano drug delivery systems fail to enter malignant brain tumors due to a
lack of proper targeting systems and the size increase of the nanoparticles after drug …

Polymeric nanostructures for imaging and therapy

M Elsabahy, GS Heo, SM Lim, G Sun… - Chemical …, 2015 - ACS Publications
Medical diagnosis and therapy are essential for providing patients with proper care,
although inefficient diagnosis and therapy are usually associated with either improper …

Lipid–polymer hybrid nanoparticles as a next-generation drug delivery platform: state of the art, emerging technologies, and perspectives

A Mukherjee, AK Waters, P Kalyan… - International journal …, 2019 - Taylor & Francis
Lipid–polymer hybrid nanoparticles (LPHNPs) are next-generation core–shell
nanostructures, conceptually derived from both liposome and polymeric nanoparticles …

Lipid–polymer hybrid nanoparticles as a new generation therapeutic delivery platform: a review

K Hadinoto, A Sundaresan, WS Cheow - European journal of …, 2013 - Elsevier
Lipid–polymer hybrid nanoparticles (LPNs) are core–shell nanoparticle structures
comprising polymer cores and lipid/lipid–PEG shells, which exhibit complementary …