BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module
D Park, AC Tosello-Trampont, MR Elliott, M Lu… - Nature, 2007 - nature.com
Engulfment and subsequent degradation of apoptotic cells is an essential step that occurs
throughout life in all multicellular organisms,,. ELMO/Dock180/Rac proteins are a conserved …
throughout life in all multicellular organisms,,. ELMO/Dock180/Rac proteins are a conserved …
Integrin αVβ3 Binds to the RGD Motif of Glycoprotein B of Kaposi's Sarcoma-Associated Herpesvirus and Functions as an RGD-Dependent Entry Receptor
HJ Garrigues, YE Rubinchikova, CM DiPersio… - Journal of …, 2008 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV) envelope-associated glycoprotein B (gB)
is involved in the initial steps of binding to host cells during KSHV infection. gB contains an …
is involved in the initial steps of binding to host cells during KSHV infection. gB contains an …
KSHV-initiated notch activation leads to membrane-type-1 matrix metalloproteinase-dependent lymphatic endothelial-to-mesenchymal transition
F Cheng, P Pekkonen, S Laurinavicius, N Sugiyama… - Cell host & …, 2011 - cell.com
Kaposi sarcoma (KS), an angioproliferative disease associated with Kaposi sarcoma
herpesvirus (KSHV) infection, harbors a diversity of cell types ranging from endothelial to …
herpesvirus (KSHV) infection, harbors a diversity of cell types ranging from endothelial to …
KSHV infects a subset of human tonsillar B cells, driving proliferation and plasmablast differentiation
LM Hassman, TJ Ellison… - The Journal of clinical …, 2011 - Am Soc Clin Investig
Kaposi sarcoma–associated herpesvirus (KSHV; also known as HHV8) is the causative
agent of two B cell tumors, multicentric Castleman disease (MCD) and primary effusion …
agent of two B cell tumors, multicentric Castleman disease (MCD) and primary effusion …
Upregulation of xCT by KSHV-encoded microRNAs facilitates KSHV dissemination and persistence in an environment of oxidative stress
Z Qin, E Freitas, R Sullivan, S Mohan, R Bacelieri… - PLoS …, 2010 - journals.plos.org
Upregulation of xCT, the inducible subunit of a membrane-bound amino acid transporter,
replenishes intracellular glutathione stores to maintain cell viability in an environment of …
replenishes intracellular glutathione stores to maintain cell viability in an environment of …
Kaposi's sarcoma-associated herpesvirus K3 and K5 ubiquitin E3 ligases have stage-specific immune evasion roles during lytic replication
K Brulois, Z Toth, LY Wong, P Feng, SJ Gao… - Journal of …, 2014 - Am Soc Microbiol
The downregulation of immune synapse components such as major histocompatibility
complex class I (MHC-I) and ICAM-1 is a common viral immune evasion strategy that …
complex class I (MHC-I) and ICAM-1 is a common viral immune evasion strategy that …
Rapamycin blocks production of KSHV/HHV8: insights into the anti-tumor activity of an immunosuppressant drug
Background Infection with Kaposi's sarcoma-associated herpesvirus (KSHV/HHV8) often
results in the development of fatal tumors in immunocompromised patients. Studies of renal …
results in the development of fatal tumors in immunocompromised patients. Studies of renal …
mTOR inhibitors block Kaposi sarcoma growth by inhibiting essential autocrine growth factors and tumor angiogenesis
Kaposi sarcoma originates from endothelial cells and it is one of the most overt angiogenic
tumors. In Sub-Saharan Africa, where HIV and the Kaposi sarcoma–associated herpesvirus …
tumors. In Sub-Saharan Africa, where HIV and the Kaposi sarcoma–associated herpesvirus …
RNA editing of the human herpesvirus 8 kaposin transcript eliminates its transforming activity and is induced during lytic replication
SZ Gandy, SD Linnstaedt, S Muralidhar… - Journal of …, 2007 - Am Soc Microbiol
Human herpesvirus 8 is the etiologic agent associated with Kaposi's sarcoma and primary
effusion lymphoma (PEL). The K12 RNA, which produces as many as three variants of the …
effusion lymphoma (PEL). The K12 RNA, which produces as many as three variants of the …
Kaposi's sarcoma-associated herpesvirus gH/gL: glycoprotein export and interaction with cellular receptors
A Hahn, A Birkmann, E Wies, D Dorer, K Mahr… - Journal of …, 2009 - Am Soc Microbiol
The attachment, entry, and fusion of Kaposi's sarcoma-associated herpesvirus (KSHV) with
target cells are mediated by complex machinery containing, among others, viral glycoprotein …
target cells are mediated by complex machinery containing, among others, viral glycoprotein …