For more than 60 years dequalinium chloride (DQ) has been used as anti-infective drug,
mainly to treat local infections. It is a standard drug to treat bacterial vaginosis and an active …

Cyclic nucleotide-gated (CNG) ion channels play a central role in vision and olfaction,
generating the electrical responses to light in photoreceptors and to odorants in olfactory …

Mycothiol ligase (MshC) is a key enzyme in the biosynthesis of mycothiol, a small molecular
weight thiol that is unique to actinomycetes and whose primary role is to maintain …

Cyclic nucleotide-gated (CNG) channels mediate transduction in several sensory neurons.
These channels use the free energy of CNs' binding to open the pore, a process referred to …

Cyclic nucleotide-gated (CNG) channels play important roles in the transduction of visual
and olfactory information by sensing changes in the intracellular concentration of cyclic …

Cyclic nucleotide–gated (CNG) ion channels are nonselective cation channels with a high
permeability for Ca2+. Not surprisingly, they are blocked by a number of Ca2+ channel …

Ion channels that are principally activated by direct binding of intracellular cyclic nucleotides
have evolved as cation nonselective transducers for intracellular pathways that regulate …

Rod vision begins when 11-cis-retinal absorbs a photon and isomerizes to all-trans-retinal
(ATR) within the photopigment, rhodopsin. Photoactivated rhodopsin triggers an enzyme …

Trajectories of a signal that fluctuates between two states which originate from single
molecule activities have become ubiquitous. Common examples are trajectories of ionic flux …

Rod vision is initiated when 11-cis-retinal, bound within rhodopsin, absorbs a photon and
isomerizes to all-trans-retinal (ATR). This triggers an enzyme cascade that lowers cGMP …