The direct transformation of methane to methanol remains a significant challenge for
operation at a larger scale. Central to this challenge is the low reactivity of methane at …

Native mass spectrometry (MS) involves the analysis and characterization of
macromolecules, predominantly intact proteins and protein complexes, whereby as much as …

Nature's primary methane-oxidizing enzyme, the membrane-bound particulate methane
monooxygenase (pMMO), catalyses the oxidation of methane to methanol. Copper is …

Bacterial methane oxidation using the enzyme particulate methane monooxygenase
(pMMO) contributes to the removal of environmental methane, a potent greenhouse gas …

Methanotrophic bacteria represent a potential route to methane utilization and mitigation of
methane emissions. In the first step of their metabolic pathway, aerobic methanotrophs use …

Biological membranes formed of amphipathic lipid bilayers provide chemical barriers to
separate cells from their external environments and define subcellular compartments …

Membrane proteins are involved in numerous vital biological processes, including transport,
signal transduction and the enzymes in a variety of metabolic pathways. Integral membrane …

In biology, it can be argued that if the genome contains the script for a cell's life cycle, then
the proteome constitutes an ensemble cast of actors that brings these instructions to life …

Methane is a potent greenhouse gas that contributes significantly to climate change and is
primarily regulated in Nature by methanotrophic bacteria, which consume methane gas as …

Particulate methane monooxygenase (pMMO) plays a critical role in catalyzing the
conversion of methane to methanol, constituting the initial step in the C1 metabolic pathway …