Diabetes and beta cell function: from mechanisms to evaluation and clinical implications

S Cernea, M Dobreanu - Biochemia medica, 2013 - hrcak.srce.hr
Sažetak Diabetes is a complex, heterogeneous condition that has beta cell dysfunction at its
core. Many factors (eg hyperglycemia/glucotoxicity, lipotoxicity, autoimmunity, inflammation …

Endothelial function and dysfunction: Impact of metformin

A Nafisa, SG Gray, Y Cao, T Wang, S Xu… - Pharmacology & …, 2018 - Elsevier
Cardiovascular and metabolic diseases remain the leading cause of morbidity and mortality
worldwide. Endothelial dysfunction is a key player in the initiation and progression of …

Effects of green tea extract on insulin resistance and glucagon-like peptide 1 in patients with type 2 diabetes and lipid abnormalities: a randomized, double-blinded …

CY Liu, CJ Huang, LH Huang, IJ Chen, JP Chiu… - PLoS …, 2014 - journals.plos.org
The aim of this study is to investigate the effect of green tea extract on patients with type 2
diabetes mellitus and lipid abnormalities on glycemic and lipid profiles, and hormone …

[HTML][HTML] Management of type 2 diabetes: current strategies, unfocussed aspects, challenges, and alternatives

SP Borse, AS Chhipa, V Sharma, DP Singh… - Medical Principles and …, 2021 - karger.com
Type 2 diabetes mellitus (T2DM) accounts for> 90% of the cases of diabetes in adults.
Resistance to insulin action is the major cause that leads to chronic hyperglycemia in …

Differential acute postprandial effects of processed meat and isocaloric vegan meals on the gastrointestinal hormone response in subjects suffering from type 2 …

L Belinova, H Kahleova, H Malinska, O Topolcan… - PloS one, 2014 - journals.plos.org
Background The intake of meat, particularly processed meat, is a dietary risk factor for
diabetes. Meat intake impairs insulin sensitivity and leads to increased oxidative stress …

The incretin system ABCs in obesity and diabetes–novel therapeutic strategies for weight loss and beyond

AL Joao, F Reis, R Fernandes - obesity reviews, 2016 - Wiley Online Library
Incretins are gastrointestinal‐derived hormones released in response to a meal playing a
key role in the regulation of postprandial secretion of insulin (incretin effect) and glucagon by …

[HTML][HTML] Antinociceptive behavior, glutamine/glutamate, and neopterin in early-stage streptozotocin-induced diabetic neuropathy in liraglutide-treated mice under a …

P Gateva, M Hristov, N Ivanova, D Vasileva… - International Journal of …, 2024 - mdpi.com
Diabetic neuropathy (DN) is a common complication of long-lasting type 1 and type 2
diabetes, with no curative treatment available. Here, we tested the effect of the incretin …

Correlation between baseline characteristics and clinical outcomes in a large population of diabetes patients treated with liraglutide in a real-world setting in Italy

A Lapolla, V Frison, M Bettio, M Dal Pos, P Rocchini… - Clinical …, 2015 - Elsevier
Purpose Treatment with liraglutide in randomized controlled trials is associated with
significant reductions in glycated hemoglobin (HbA 1c) and weight loss in type 2 diabetes …

Effect of combined therapy of human Wharton's jelly-derived mesenchymal stem cells from umbilical cord with sitagliptin in type 2 diabetic rats

J Hu, F Wang, R Sun, Z Wang, X Yu, L Wang, H Gao… - Endocrine, 2014 - Springer
Type 2 diabetes mellitus is the most common endocrine disease all over the world, while
existing therapies can only ameliorate hyperglycemia or temporarily improve the response …

[HTML][HTML] Benefits of healthy adipose tissue in the treatment of diabetes

SC Gunawardana - World Journal of Diabetes, 2014 - ncbi.nlm.nih.gov
The major malfunction in diabetes mellitus is severe perturbation of glucose homeostasis
caused by deficiency of insulin. Insulin deficiency is either absolute due to destruction or …