How many cell types are in the kidney and what do they do?
The kidney maintains electrolyte, water, and acid-base balance, eliminates foreign and
waste compounds, regulates blood pressure, and secretes hormones. There are at least 16 …
waste compounds, regulates blood pressure, and secretes hormones. There are at least 16 …
Insights into glomerular filtration and albuminuria
Glomerular Filtration and Albuminuria Chronic kidney diseases generally arise from a
disordered kidney filtration barrier within glomeruli. This review describes the roles of …
disordered kidney filtration barrier within glomeruli. This review describes the roles of …
Molecular mechanism of VEGF and its role in pathological angiogenesis
Over the last seven decades, a significant scientific contribution took place in the delineation
of the implications of vascular endothelial‐derived growth factor (VEGF) in the processes of …
of the implications of vascular endothelial‐derived growth factor (VEGF) in the processes of …
Diabetic microvascular disease: an endocrine society scientific statement
EJ Barrett, Z Liu, M Khamaisi, GL King… - The Journal of …, 2017 - academic.oup.com
Both type 1 and type 2 diabetes adversely affect the microvasculature in multiple organs.
Our understanding of the genesis of this injury and of potential interventions to prevent, limit …
Our understanding of the genesis of this injury and of potential interventions to prevent, limit …
[HTML][HTML] Diabetes mellitus—Progress and opportunities in the evolving epidemic
Diabetes, a complex multisystem metabolic disorder characterized by hyperglycemia, leads
to complications that reduce quality of life and increase mortality. Diabetes pathophysiology …
to complications that reduce quality of life and increase mortality. Diabetes pathophysiology …
Pre-eclampsia part 1: current understanding of its pathophysiology
Pre-eclampsia is characterized by new-onset hypertension and proteinuria at≥ 20 weeks of
gestation. In the absence of proteinuria, hypertension together with evidence of systemic …
gestation. In the absence of proteinuria, hypertension together with evidence of systemic …
Preeclampsia: maternal systemic vascular disorder caused by generalized endothelial dysfunction due to placental antiangiogenic factors
T Tomimatsu, K Mimura, S Matsuzaki, M Endo… - International journal of …, 2019 - mdpi.com
Preeclampsia, a systemic vascular disorder characterized by new-onset hypertension and
proteinuria after 20 weeks of gestation, is the leading cause of maternal and perinatal …
proteinuria after 20 weeks of gestation, is the leading cause of maternal and perinatal …
Generation of human PSC-derived kidney organoids with patterned nephron segments and a de novo vascular network
Human pluripotent stem cell-derived kidney organoids recapitulate developmental
processes and tissue architecture, but intrinsic limitations, such as lack of vasculature and …
processes and tissue architecture, but intrinsic limitations, such as lack of vasculature and …
Preeclampsia: Pathophysiology and management
Preeclampsia is a pregnancy-related multisystem disorder, frequently encountered
pregnancy-related medical complications next to gestational diabetes mellitus. It is the onset …
pregnancy-related medical complications next to gestational diabetes mellitus. It is the onset …
Mechanisms of VEGF (vascular endothelial growth factor) inhibitor–associated hypertension and vascular disease
e2 Hypertension February 2018 target> 1 kinase receptor allowing for a broader indication
for use but with a greater potential for off-target effects. VSP inhibitors have been …
for use but with a greater potential for off-target effects. VSP inhibitors have been …