Bias can arise because of the actions of primary study investigators or because of the
actions of review authors, or may be unavoidable due to constraints on how research can be …

Background An increasing amount of assistive technology interventions exist for
adolescents and adults with learning disabilities, but there has been no systematic review of …

Objective To assess the efficacy and safety of vaginal progesterone to prevent recurrent
preterm birth and adverse perinatal outcomes in singleton gestations with a history of …

The ability to accurately predict violence and other forms of serious antisocial behavior
would provide important societal benefits, and there is substantial enthusiasm for the …

Objectives Meta-analyses inform clinical practice by summarizing treatment effect estimates
based on results from several trials. However, the statistical significance of a meta-analysis …

Study preregistration promotes transparency in scientific research by making a clear
distinction between a priori and post hoc procedures or analyses. Management and applied …

Background Prospective trial registration is a powerful tool to prevent reporting bias. We
aimed to determine the extent to which published randomized controlled trials (RCTs) were …

Preregistration and registered reports are two promising open science practices for
increasing transparency in the scientific process. In particular, they create transparency …

Objectives To evaluate the compliance with prospective registration and inclusion of the trial
registration number (TRN) in published randomised controlled trials (RCTs), and to analyse …

Background A number of methods for deciding when a systematic review should be updated
have been proposed, yet little is known about whether systematic reviews are updated more …