Diagnosis and management of bone fragility in diabetes: an emerging challenge

SL Ferrari, B Abrahamsen, N Napoli, K Akesson… - Osteoporosis …, 2018 - Springer
Fragility fractures are increasingly recognized as a complication of both type 1 and type 2
diabetes, with fracture risk that increases with disease duration and poor glycemic control …

The challenges of diagnosing osteoporosis and the limitations of currently available tools

P Choksi, KJ Jepsen, GA Clines - Clinical diabetes and endocrinology, 2018 - Springer
Dual-energy X-ray absorptiometry (DXA) was the first imaging tool widely utilized by
clinicians to assess fracture risk, especially in postmenopausal women. The development of …

Inclusion health: addressing the causes of the causes

M Marmot - The Lancet, 2018 - thelancet.com
that would require many years of an antiresorptive drug treatment alone. 16, 17 In a direct
comparator trial18 of romosozumab or alendronate for 1 year, followed by alendronate for 2 …

The clinical application of high-resolution peripheral computed tomography (HR-pQCT) in adults: state of the art and future directions

JP Van den Bergh, P Szulc, AM Cheung… - Osteoporosis …, 2021 - Springer
High-resolution peripheral computed tomography (HR-pQCT) was developed to image bone
microarchitecture in vivo at peripheral skeletal sites. Since the introduction of HR-pQCT in …

Effects of abaloparatide, a human parathyroid hormone-related peptide analog, on bone mineral density in postmenopausal women with osteoporosis

BZ Leder, LSL O'Dea, JR Zanchetta… - The Journal of …, 2015 - academic.oup.com
Context: Abaloparatide is a novel synthetic peptide analog of parathyroid hormone-related
protein (PTHrP) that is currently being developed as a potential anabolic agent in the …

Teriparatide for osteoporosis: importance of the full course

R Lindsay, JH Krege, F Marin, L Jin… - Osteoporosis international, 2016 - Springer
Teriparatide (TPTD) is the only currently available therapeutic agent that increases the
formation of new bone tissue and can provide some remediation of the architectural defects …

High-resolution peripheral quantitative computed tomography for the assessment of bone strength and structure: a review by the Canadian Bone Strength Working …

AM Cheung, JD Adachi, DA Hanley, DL Kendler… - Current osteoporosis …, 2013 - Springer
Bone structure is an integral determinant of bone strength. The availability of high resolution
peripheral quantitative computed tomography (HR-pQCT) has made it possible to measure …

The male athlete triad—a consensus statement from the Female and Male Athlete Triad Coalition part II: diagnosis, treatment, and return-to-play

M Fredericson, A Kussman, M Misra… - Clinical Journal of …, 2021 - journals.lww.com
Abstract The Male Athlete Triad is a medical syndrome most common in adolescent and
young adult male athletes in sports that emphasize a lean physique, especially endurance …

Bone geometry, volumetric density, microarchitecture, and estimated bone strength assessed by HR‐pQCT in adult patients with type 1 diabetes mellitus

VV Shanbhogue, S Hansen, M Frost… - Journal of bone and …, 2015 - academic.oup.com
The primary goal of this cross‐sectional in vivo study was to assess peripheral bone
microarchitecture, bone strength, and bone remodeling in adult type 1 diabetes (T1D) …

Cortical and trabecular bone microstructure did not recover at weight‐bearing skeletal sites and progressively deteriorated at non‐weight‐bearing sites during the …

L Vico, B van Rietbergen, N Vilayphiou… - Journal of Bone and …, 2017 - academic.oup.com
Risk for premature osteoporosis is a major health concern in astronauts and cosmonauts;
the reversibility of the bone lost at the weight‐bearing bone sites is not established, although …