Objectives To provide a summary of evidence for the diagnostic accuracies of three
multiplex PCR systems (mPCRs)—BioFire FilmArray RP (FilmArray), Nanosphere Verigene …

Respiratory viral infections are associated with a wide range of acute syndromes and
infectious disease processes in children and adults worldwide. Many viruses are implicated …

Biomedical engineers have traditionally developed technologies in response to the needs of
the developed world's medical community. As a result, the diagnostic systems on which they …

The ideal clinical diagnostic system should deliver rapid, sensitive, specific and reproducible
results while minimizing the requirements for specialized laboratory facilities and skilled …

The introduction of in vitro nucleic acid amplification techniques, led by real-time PCR, into
the clinical microbiology laboratory has transformed the laboratory detection of viruses and …

Clinical laboratories historically diagnose seven or eight respiratory virus infections using a
combination of techniques including enzyme immunoassay, direct fluorescent antibody …

The appearance of eight new respiratory viruses, including the SARS coronavirus in 2003
and swine-origin influenza A/H1N1 in 2009, in the human population in the past nine years …

Molecular methods are becoming more widely used for the detection of respiratory
pathogens, in part because of their superior sensitivity, relatively rapid turnaround time, and …

We randomized 115 children to trivalent inactivated influenza vaccine (TIV) or placebo. Over
the following 9 months, TIV recipients had an increased risk of virologically-confirmed non …

Viral infectious diseases represent a major threat to public health and are among the
greatest disease burdens worldwide. Rapid and accurate identification of viral agents is …