[HTML][HTML] Efficacy of biologic drugs in short-duration versus long-duration inflammatory bowel disease: a systematic review and an individual-patient data meta-analysis …

S Ben-Horin, L Novack, R Mao, J Guo, Y Zhao… - Gastroenterology, 2022 - Elsevier
Background and Aims Starting biologic treatment early in the course of inflammatory bowel
disease (IBD) may be associated with higher efficacy, especially in Crohn's disease (CD) …

Lifestyle, behaviour, and environmental modification for the management of patients with inflammatory bowel diseases: an International Organization for Study of …

AN Ananthakrishnan, GG Kaplan… - The lancet …, 2022 - thelancet.com
Environmental and lifestyle factors play an important role in the natural history of Crohn's
disease and ulcerative colitis. A group of international experts from the International …

Metaproteomics reveals diet-induced changes in gut microbiome function according to Crohn's disease location

S Levi Mortera, V Marzano, F Rapisarda, C Marangelo… - Microbiome, 2024 - Springer
Background Crohn's disease (CD) is characterized by chronic intestinal inflammation. Diet is
a key modifiable factor influencing the gut microbiome (GM) and a risk factor for CD …

Faecal myeloperoxidase as a biomarker of endoscopic activity in inflammatory bowel disease

A Swaminathan, GM Borichevsky… - Journal of Crohn's …, 2022 - academic.oup.com
Abstract Background and Aims Inflammatory bowel disease [IBD], consisting of Crohn's
disease [CD] and ulcerative colitis [UC], is a relapsing-remitting illness. Treat-to-target IBD …

Predicting diagnostic biomarkers associated with immune infiltration in Crohn's disease based on machine learning and bioinformatics

W Bao, L Wang, X Liu, M Li - European Journal of Medical Research, 2023 - Springer
Objective The objective of this study is to investigate potential biomarkers of Crohn's disease
(CD) and the pathological importance of infiltration of associated immune cells in disease …

[HTML][HTML] Ileal and colonic Crohn's disease: Does location makes a difference in therapy efficacy?

R Atreya, C Bojarski, AA Kühl, Z Trajanoski… - Current research in …, 2022 - Elsevier
Within the IBD entity of Crohn's disease, there is currently no differentiation between ileal
and colonic manifestation for recruitment of patients in clinical trials, well-powered analysis …

Dysregulation of intestinal epithelial electrolyte transport in canine chronic inflammatory enteropathy and the role of the renin-angiotensin-aldosterone-system

F Dengler, O Domenig, S Kather… - Frontiers in Veterinary …, 2023 - frontiersin.org
Chronic diarrhea is a hallmark sign of canine chronic inflammatory enteropathy (CIE),
leading to fluid and electrolyte losses. Electrolyte homeostasis is regulated by the renin …

Spatial features of skip lesions in Crohn's disease

R Herren, N Geva-Zatorsky - Trends in Immunology, 2024 - cell.com
Skip lesions are an enigmatic spatial feature characterizing Crohn's disease (CD). They
comprise inflamed and adjacent non-inflamed tissue sections with a clear demarcation …

Exploring the intestinal ecosystem: from gut microbiota to associations with subtypes of inflammatory bowel disease

F Li, C Yu, Q Zhao, Z Wang, Z Wang… - Frontiers in Cellular …, 2024 - frontiersin.org
Objective Significant differences have been discovered between subtypes of Crohn's
disease (CD) and ulcerative colitis (UC). The role of gut microbiota in promoting the onset of …

From serum metabolites to the gut: revealing metabolic clues to susceptibility to subtypes of Crohn's disease and ulcerative colitis

F Li, Z Wang, T Tang, Q Zhao, Z Wang, X Han… - Frontiers in …, 2024 - frontiersin.org
Background and aims Inflammatory bowel disease (IBD) is a common chronic inflammatory
bowel disease characterized by diarrhea and abdominal pain. Recently human metabolites …