Tutorial on MUedit: An open-source software for identifying and analysing the discharge timing of motor units from electromyographic signals

S Avrillon, F Hug, SN Baker, C Gibbs… - … of Electromyography and …, 2024 - Elsevier
We introduce the open-source software MUedit and we describe its use for identifying the
discharge timing of motor units from all types of electromyographic (EMG) signals recorded …

Motoneuron-driven computational muscle modelling with motor unit resolution and subject-specific musculoskeletal anatomy

AH Caillet, ATM Phillips, D Farina… - PLOS Computational …, 2023 - journals.plos.org
The computational simulation of human voluntary muscle contraction is possible with EMG-
driven Hill-type models of whole muscles. Despite impactful applications in numerous fields …

[HTML][HTML] I-Spin live: An open-source software based on blind-source separation for decoding the activity of spinal alpha motor neurons in real-time

J Rossato, F Hug, K Tucker, L Lacourpaille, D Farina… - Elife, 2023 - elifesciences.org
Decoding the activity of individual neural cells during natural behaviours allows
neuroscientists to study how the nervous system generates and controls movements …

Influence of spatio-temporal filtering on hand kinematics estimation from high-density EMG signals

RC Sîmpetru, V Cnejevici, D Farina… - Journal of Neural …, 2024 - iopscience.iop.org
Objective. Surface electromyography (sEMG) is a non-invasive technique that records the
electrical signals generated by muscles through electrodes placed on the skin. sEMG is the …

The decoding of extensive samples of motor units in human muscles reveals the rate coding of entire motoneuron pools

S Avrillon, F Hug, R Enoka, AH Caillet, D Farina - Biorxiv, 2023 - biorxiv.org
To advance our understanding of the neural control of muscle, we decoded the firing activity
of extensive samples of motor units in the Tibialis Anterior (129±44 per participant; n= 8) and …

The identification of extensive samples of motor units in human muscles reveals diverse effects of neuromodulatory inputs on the rate coding

S Avrillon, F Hug, RM Enoka, AHD Caillet, D Farina - eLife, 2024 - elifesciences.org
Movements are performed by motoneurons transforming synaptic inputs into an activation
signal that controls muscle force. The control signal emerges from interactions between …

I-Spin live, an open-source software based on blind-source separation for real-time decoding of motor unit activity in humans

J Rossato, F Hug, K Tucker, C Gibbs, L Lacourpaille… - eLife, 2024 - elifesciences.org
Decoding the activity of individual neural cells during natural behaviours allows
neuroscientists to study how the nervous system generates and controls movements …

Human motor unit discharge patterns reveal differences in neuromodulatory and inhibitory drive to motoneurons across contraction levels

J Škarabot, JA Beauchamp, GEP Pearcey - bioRxiv, 2023 - biorxiv.org
Transformation of motor commands via a motor unit (MU) into mechanical actions of muscle
fibres is a non-linear function influenced by ionotropic excitatory/inhibitory and …

[HTML][HTML] OpenDiHu: an efficient and scalable framework for biophysical simulations of the neuromuscular system

B Maier, D Göddeke, F Huber, T Klotz, O Röhrle… - Journal of …, 2024 - Elsevier
The versatile neuromuscular system, consisting of skeletal muscles and the nervous system,
enables human to perform crucial everyday tasks. To investigate its functioning and …

Intrinsic motoneuron properties in typical human development

G Mohammadalinejad, B Afsharipour… - The Journal of …, 2024 - Wiley Online Library
Motoneuron properties and their firing patterns undergo significant changes throughout
development and in response to neuromodulators such as serotonin. Here, we examined …