Adolescence is a particularly vulnerable neurodevelopmental period marked by high rates
of engagement with risky alcohol use. This review summarizes the cognitive and neural …

Sex differences may play a critical role in modulating how chronic or heavy alcohol use
impacts the brain to cause the development of alcohol use disorder (AUD). AUD is a …

In the past quarter century, emotion dysregulation has emerged as an increasingly important
construct for understanding diverse adjustment problems in childhood, adolescence, and …

Adolescence is an important ontogenetic period that is characterized by behaviors such as
enhanced novelty-seeking, impulsivity, and reward preference, which can give rise to an …

Substance use disorders (SUDs) manifest as chronic relapsing disorders, characterized by
compulsive drug taking despite serious adverse consequences, the loss of control over …

This review provides the first systematic and quantitative synthesis of the literature
examining the relationship between binge drinking, cognition, brain structure and function in …

Alcohol use and misuse is increasing among women. Although the prevalence of drinking
remains higher in men than women, the gender gap is narrowing. This narrative review …

PURPOSE Alcohol and cannabis are the most commonly used substances during
adolescence and are typically initiated during this sensitive neurodevelopmental period. The …

Addictions are heritable and unfold dynamically across the lifespan. One prominent
neurobiological theory proposes that substance-induced changes in neural circuitry promote …

Early life stress (ELS) is a well-established risk factor for many psychiatric and medical
disorders, including substance use disorders (SUDs). The relationship between ELS and …