The role of inhibitory circuits in hippocampal memory processing

L Topolnik, S Tamboli - Nature Reviews Neuroscience, 2022 - nature.com
GABAergic inhibitory circuits play an essential role in coordinating various hippocampal
functions. Several decades of work dedicated to a thorough characterization of hippocampal …

[HTML][HTML] Hippocampal GABAergic interneurons and memory

A Tzilivaki, JJ Tukker, N Maier, P Poirazi, RP Sammons… - Neuron, 2023 - cell.com
One of the most captivating questions in neuroscience revolves around the brain's ability to
efficiently and durably capture and store information. It must process continuous input from …

[HTML][HTML] A transcriptomic axis predicts state modulation of cortical interneurons

S Bugeon, J Duffield, M Dipoppa, A Ritoux, I Prankerd… - Nature, 2022 - nature.com
Transcriptomics has revealed that cortical inhibitory neurons exhibit a great diversity of fine
molecular subtypes,,,,–, but it is not known whether these subtypes have correspondingly …

[HTML][HTML] Recruitment and inhibitory action of hippocampal axo-axonic cells during behavior

B Dudok, M Szoboszlay, A Paul, PM Klein, Z Liao… - Neuron, 2021 - cell.com
The axon initial segment of hippocampal pyramidal cells is a key subcellular compartment
for action potential generation, under GABAergic control by the" chandelier" or axo-axonic …

Inhibitory control of sharp-wave ripple duration during learning in hippocampal recurrent networks

B Vancura, T Geiller, A Grosmark, V Zhao… - Nature …, 2023 - nature.com
Recurrent excitatory connections in hippocampal regions CA3 and CA2 are thought to play
a key role in the generation of sharp-wave ripples (SWRs), electrophysiological oscillations …

Cell-type-specific inhibitory circuitry from a connectomic census of mouse visual cortex

CM Schneider-Mizell, AL Bodor, D Brittain… - …, 2024 - pmc.ncbi.nlm.nih.gov
Mammalian cortex features a vast diversity of neuronal cell types, each with characteristic
anatomical, molecular and functional properties. Synaptic connectivity powerfully shapes …

Subfield-specific interneuron circuits govern the hippocampal response to novelty in male mice

T Hainmueller, A Cazala, LW Huang… - Nature …, 2024 - nature.com
The hippocampus is the brain's center for episodic memories. Its subregions, the dentate
gyrus and CA1-3, are differentially involved in memory encoding and recall. Hippocampal …

The cell-type underpinnings of the human functional cortical connectome

XH Zhang, KM Anderson, HM Dong, S Chopra… - Nature …, 2024 - nature.com
The functional properties of the human brain arise, in part, from the vast assortment of cell
types that pattern the cerebral cortex. The cortical sheet can be broadly divided into distinct …

A hippocampal circuit mechanism to balance memory reactivation during sleep

LA Karaba, HL Robinson, RE Harvey, W Chen… - Science, 2024 - science.org
Memory consolidation involves the synchronous reactivation of hippocampal cells active
during recent experience in sleep sharp-wave ripples (SWRs). How this increase in firing …

Id2 GABAergic interneurons comprise a neglected fourth major group of cortical inhibitory cells

R Machold, S Dellal, M Valero, H Zurita, I Kruglikov… - elife, 2023 - elifesciences.org
Abstract Cortical GABAergic interneurons (INs) represent a diverse population of mainly
locally projecting cells that provide specialized forms of inhibition to pyramidal neurons and …