Synthesis, characterization, DNA photocleavage, in silico and in vitro DNA/BSA binding properties of novel hexahydroquinolines

MA Ragheb, RS Omar, MH Soliman… - Journal of Molecular …, 2022 - Elsevier
A simple, and efficient procedure has been developed for the synthesis of novel 2-(4-
(hexahydroquinolin-4-yl) phenoxy)-N-arylacetamides and thieno [3′, 2′: 5, 6] pyrimido [1 …

Hantzsch‐like synthesis, DNA photocleavage, DNA/BSA binding, and molecular docking studies of bis (sulfanediyl) bis (tetrahydro‐5‐deazaflavin) analogs linked to …

MA Ragheb, RE Abdelwahab… - Chemistry & …, 2022 - Wiley Online Library
The cyclocondensation reaction of aldehydes with dimedone and bis (6‐aminopyrimidin‐4‐
one) in acetic acid led to the formation of the corresponding bis (pyrimido [4, 5‐b] quinoline …

Pyridine‐2(1H)‐thiones: Versatile Precursors for Novel Pyrazolo[3,4‐b]pyridine, Thieno[2,3‐b]pyridines, and Their Fused Azines

SMH Sanad, AM Abdel‐Fattah… - Journal of …, 2019 - Wiley Online Library
Pyridine‐2 (1H)‐thiones were prepared and reacted with several active halogenated
reagents to afford novel thieno [2, 3‐b] pyridines in excellent yields. Thieno [2, 3‐b] pyridine …

Dimroth's Rearrangement as a Synthetic Strategy Towards New Heterocyclic Compounds

VF Ferreira, T de B da Silva, FP Pauli… - Current Organic …, 2020 - ingentaconnect.com
Molecular rearrangements are important tools to increase the molecular diversity of new
bioactive compounds, especially in the class of heterocycles. This review deals specifically …

Synthesis and characterization of novel bis(pyridine-2(1H)-thiones) and their bis(2-methylsulfanylpyridines) incorporating 2,6-dibromophenoxy moiety

SMH Sanad, AM Abdel-Fattah, FA Attaby… - Canadian Journal of …, 2019 - cdnsciencepub.com
The novel 1, 4-bis (2, 6-dibromo-4-formylphenoxy) butane (3), prepared from 3, 5-
dibromobenzaldehyde (1), reacted with different hydrazines 4a–4d and active methylene …

Utility of Pyridine‐2(1H)‐thiones in the Synthesis of Novel Bis‐Thieno[2,3‐b]pyridines and Their Fused Azines

SMH Sanad, AM Abdel‐Fattah… - Journal of …, 2019 - Wiley Online Library
The starting materials pyridine‐2 (1H)‐thiones are prepared and reacted with halogen‐
containing reagents in ethanolic sodium acetate solution to give the corresponding 2‐S …

Catalyst-free synthesis of highly functionalized triazole hexahydroquinoline carbohydrazide scaffolds via four-component cyclocondensation reaction

H Amorzesh, M Bayat, S Nasri - Molecular Diversity, 2024 - Springer
A new class of multi-functional triazole hexahydroquinoline carbohydrazide named 2-amino-
7, 7-dimethyl-5-oxo-4-phenyl-1-(4 H-1, 2, 4-triazol-3-yl)-1, 4, 5, 6, 7, 8-hexahydroquinoline-3 …

[PDF][PDF] Synthesis of spiroindolines on the basis of isatylidene malononitrile

AM Magerramov, FN Naghiyev… - Russian Journal of …, 2018 - academia.edu
Synthesis of Spiroindolines on the Basis of Isatylidene Malononitrile Page 1 ### Synthesis of
Spiroindolines on the Basis of Isatylidene Malononitrile AM Magerramova, FN Nagieva,* GZ …

Hantzsch reaction with bis-indole-2, 3-diones: Synthesis of novel bis-spirocyclic oxindole incorporating acridine, dipyrazolo [3, 4-b: 4', 3'-e] pyridine and pyrido [2, 3-d …

AM Abdelmoniem, MGM Abdelrahman… - Synthetic …, 2021 - Taylor & Francis
One-pot three-component cyclo-condensation reaction of bis (indole-2, 3-diones) with
dimedone, 3-methyl-1 H-pyrazol-5 (4 H)-one, or 6-aminouracil in boiling acetic acid afforded …

Novel one‐pot synthesis of imidazo[2,1‐b] [1, 2, 4]‐Triazoles, 1,2,4‐Triazolo iminoindoline‐2‐ones, and their in‐vitro antibacterial activity, B‐DNA study

P Venkatesham, SR Parcha, SL Rath… - Journal of …, 2023 - Wiley Online Library
Abstract New series of 2‐(benzylthio)‐6‐phenyl‐4 H‐imidazo [1, 2‐b][1, 2, 4]‐Triazoles and
benzylthio‐4 H‐1, 2, 4‐Triazolo iminoimdoline‐2‐ones have been synthesized via a one …