HIV associated neurodegenerative disorders: a new perspective on the role of lipid rafts in Gp120-mediated neurotoxicity
The implementation of combination antiretroviral therapy (cART) as the primary means of
treatment for HIV infection has achieved a dramatic decline in deaths attributed to AIDS and …
treatment for HIV infection has achieved a dramatic decline in deaths attributed to AIDS and …
A systematic study of the N-glycosylation sites of HIV-1 envelope protein on infectivity and antibody-mediated neutralization
W Wang, J Nie, C Prochnow, C Truong, Z Jia, S Wang… - Retrovirology, 2013 - Springer
Background Glycans on the human immunodeficiency virus (HIV) envelope glycoprotein
(Env) play an important role in viral infection and evasion of neutralization by antibodies. In …
(Env) play an important role in viral infection and evasion of neutralization by antibodies. In …
Comparison of antibody-dependent cell-mediated cytotoxicity and virus neutralization by HIV-1 Env-specific monoclonal antibodies
B von Bredow, JF Arias, LN Heyer, B Moldt… - Journal of …, 2016 - Am Soc Microbiol
Although antibodies to the human immunodeficiency virus type 1 (HIV-1) envelope
glycoprotein have been studied extensively for their ability to block viral infectivity, little data …
glycoprotein have been studied extensively for their ability to block viral infectivity, little data …
HIV-1 envelope and MPER antibody structures in lipid assemblies
Structural and functional studies of HIV envelope glycoprotein (Env) as a transmembrane
protein have long been complicated by challenges associated with inherent flexibility of the …
protein have long been complicated by challenges associated with inherent flexibility of the …
Characterization of the human immunodeficiency virus (HIV-1) envelope glycoprotein conformational states on infectious virus particles
ABSTRACT Human immunodeficiency virus (HIV-1) entry into cells involves triggering of the
viral envelope glycoprotein (Env) trimer ([gp120/gp41] 3) by the primary receptor, CD4, and …
viral envelope glycoprotein (Env) trimer ([gp120/gp41] 3) by the primary receptor, CD4, and …
The cytoplasmic tail of retroviral envelope glycoproteins
PR Tedbury, EO Freed - Progress in molecular biology and translational …, 2015 - Elsevier
Retroviruses comprise a large, diverse group that infects a broad range of host organisms.
Pathogenicity varies widely; the human immunodeficiency virus is the causative agent of …
Pathogenicity varies widely; the human immunodeficiency virus is the causative agent of …
[HTML][HTML] A comparative immunogenicity study of HIV-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble …
ET Crooks, PL Moore, M Franti, CS Cayanan, P Zhu… - Virology, 2007 - Elsevier
To assess the potential of native Envelope glycoprotein (Env) trimers as neutralizing
antibody vaccines, we immunized guinea pigs with three types of VLPs and soluble gp120 …
antibody vaccines, we immunized guinea pigs with three types of VLPs and soluble gp120 …
The lipid membrane of HIV-1 stabilizes the viral envelope glycoproteins and modulates their sensitivity to antibody neutralization
H Salimi, J Johnson, MG Flores, MS Zhang… - Journal of Biological …, 2020 - ASBMB
The envelope glycoproteins (Envs) of HIV-1 are embedded in the cholesterol-rich lipid
membrane of the virus. Chemical depletion of cholesterol from HIV-1 particles inactivates …
membrane of the virus. Chemical depletion of cholesterol from HIV-1 particles inactivates …
Role of the membrane-spanning domain of human immunodeficiency virus type 1 envelope glycoprotein in cell-cell fusion and virus infection
The membrane-spanning domain (MSD) of the human immunodeficiency virus type 1 (HIV-
1) gp41 glycoprotein is critical for its biological activity. Previous C-terminal truncation …
1) gp41 glycoprotein is critical for its biological activity. Previous C-terminal truncation …
[HTML][HTML] A replication-incompetent Rift Valley fever vaccine: chimeric virus-like particles protect mice and rats against lethal challenge
RB Mandell, R Koukuntla, LJK Mogler, AK Carzoli… - Virology, 2010 - Elsevier
Virus-like particles (VLPs) present viral antigens in a native conformation and are effectively
recognized by the immune system and therefore are considered as suitable and safe …
recognized by the immune system and therefore are considered as suitable and safe …