The natural compound plumbagin has a wide range of pharmacological and potential
therapeutic activities, although its role in neuroretina degeneration is unknown. Here we …

Microtubule affinity regulating kinase 4 (MARK4) is associated with the progression of
neurodegeneration, cancer, cardiovascular diseases, obesity and other life-threatening …

Introduction Bioactive elements present in distinct medicinal plants and foods are appealing
molecules for the evolution of novel medications for the treatment of multiple illnesses linked …

The gut-brain axis is a complex bidirectional communication network between the
gastrointestinal tract and the central nervous system (CNS). The axis is crucial in …

Ethnopharmacological relevance The use and efficacy of Gynostemma [Gynostemma
pentaphyllum (Thunb.) Makino], a versatile traditional Chinese herb, was first documented in …

The cysteine residues of Keap1 such as C151, C273, and C288 are critical for its repressor
activity on Nrf2. However, to date, no molecules have been identified to covalently modify all …

This study investigated the effects of subchronic arsenic exposure on behavior, neurological
function, and hippocampal damage in rats. Thirty-two male Wistar rats were divided into four …

Background Depression is a mental illness characterized by persistent sadness and a
reduced capacity for pleasure. In clinical practice, SSRIs and other medications are …

Ketamine is a dissociative anesthetic that has been proposed to be a useful alternative in
cases of a poor response to other treatments in patients with depression. Remarkably …

目的基于网络药理学探讨白花丹素是否通过减轻焦亡来抑制脓毒症心肌损伤的机制.
方法通过网络药理学方法获得白花丹素与疾病的关键靶点, 进行GO, KEGG 分析 …