Galectin-3 is a member of the galectin family, which are β‑galactoside‑binding lectins with≥
1 evolutionary conserved carbohydrate‑recognition domain. It binds proteins in a …

Galectin-3 (Gal-3) is a 30KDa lectin implicated in multiple pathophysiology pathways
including renal damage and fibrosis. Gal-3 binds β-galactoside through its carbohydrate …

Introduction Cardiac biomarkers soluble ST2 (sST2) and galectin-3 may reflect cardiac
inflammation and fibrosis. It is plausible that these mechanisms may also contribute to the …

Background: Galectin-3 is a member of a closely related lectin family, which is detected in
several vertebrate epithelial and myeloid cell types. This beta-galactoside-binding soluble …

Galectins are evolutionary conserved β-galactoside binding proteins with a carbohydrate-
recognition domain (CRD) of approximately 130 amino acids. In mammals, 15 members of …

Asymmetrical dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase
(NOS), impairs the beneficial effect of NO. The predictive value of ADMA for all-cause …

Background Higher serum galectin-3 levels are related to adverse outcomes in different
disease states. However, the association of galectin-3 with mortality in the maintenance …

Background: Myocardial fibrosis represents a mainstay pathway in the pathophysiology of
uremic cardiomyopathy. This process leads to structural and functional changes in the heart …

Dialysis patients experience 10–20 times higher cardiovascular mortality than the general
population. The high burden of both conventional and nontraditional risk factors attributable …

Galectin-3 levels have been studied as a potential biomarker for predicting cardiovascular
(CV) risk and mortality in hemodialysis (HD) patients. Recently, a close relationship between …