Chronic low grade inflammation in pathogenesis of PCOS

E Rudnicka, K Suchta, M Grymowicz… - International journal of …, 2021 - mdpi.com
Polycystic ovary syndrome (PCOS) is a one of the most common endocrine disorders, with a
prevalence rate of 5–10% in reproductive aged women. It's characterized by (1) chronic …

[HTML][HTML] Inflammation and cardiovascular disease: From mechanisms to therapeutics

A Alfaddagh, SS Martin, TM Leucker, ED Michos… - American journal of …, 2020 - Elsevier
Inflammation constitutes a complex, highly conserved cascade of molecular and cellular
events. Inflammation has been labeled as “the fire within,” is highly regulated, and is critical …

Role of leptin in inflammation and vice versa

A Pérez-Pérez, F Sánchez-Jiménez… - International journal of …, 2020 - mdpi.com
Inflammation is an essential immune response for the maintenance of tissue homeostasis. In
a general sense, acute and chronic inflammation are different types of adaptive response …

[HTML][HTML] Obesity, osteoporosis and bone metabolism

K Gkastaris, DG Goulis, M Potoupnis… - … of musculoskeletal & …, 2020 - ncbi.nlm.nih.gov
Obesity and osteoporosis have become major global health problems over the last decades
as their prevalence is increasing. The interaction between obesity and bone metabolism is …

Obesity, oxidative stress, adipose tissue dysfunction, and the associated health risks: causes and therapeutic strategies

P Manna, SK Jain - Metabolic syndrome and related disorders, 2015 - liebertpub.com
Obesity is gaining acceptance as a serious primary health burden that impairs the quality of
life because of its associated complications, including diabetes, cardiovascular diseases …

Obesity as a risk factor for severe COVID-19 and complications: a review

F Demeulemeester, K de Punder, M van Heijningen… - Cells, 2021 - mdpi.com
Emerging data suggest that obesity is a major risk factor for the progression of major
complications such as acute respiratory distress syndrome (ARDS), cytokine storm and …

Polycystic ovary syndrome, insulin resistance, and obesity: navigating the pathophysiologic labyrinth

J Rojas, M Chávez, L Olivar, M Rojas… - International journal …, 2014 - Wiley Online Library
Polycystic ovary syndrome (PCOS) is a highly prevalent endocrine‐metabolic disorder that
implies various severe consequences to female health, including alarming rates of infertility …

The role of obesity-induced perivascular adipose tissue (PVAT) dysfunction in vascular homeostasis

A Stanek, K Brożyna-Tkaczyk, W Myśliński - Nutrients, 2021 - mdpi.com
Perivascular adipose tissue (PVAT) is an additional special type of adipose tissue
surrounding blood vessels. Under physiological conditions, PVAT plays a significant role in …

Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss

CJ Lavie, RV Milani, HO Ventura - Journal of the American college of …, 2009 - jacc.org
Obesity has reached global epidemic proportions in both adults and children and is
associated with numerous comorbidities, including hypertension (HTN), type II diabetes …

Measuring adiposity in patients: the utility of body mass index (BMI), percent body fat, and leptin

NR Shah, ER Braverman - PloS one, 2012 - journals.plos.org
Background Obesity is a serious disease that is associated with an increased risk of
diabetes, hypertension, heart disease, stroke, and cancer, among other diseases. The …