▪ Abstract During the past decade, much progress has been made in understanding how the
adult fly is built. Some old concepts such as those of compartments and selector genes have …

Molecular and genetic evidence accumulated during the past 20 years in the field of
developmental biology indicates that different animals possess many common genetic …

During animal development, distinct tissues, organs, and appendages are specified through
differential gene transcription by Hox transcription factors. However, the conserved Hox …

The evolutionarily conserved Hox gene family of transcriptional regulators has originally
been known for specifying positional identities along the longitudinal body axis of bilateral …

Despite the identification of PBC proteins as cofactors that provide DNA affinity and binding
specificity for the HOX homeodomain proteins, HOX proteins do not demonstrate robust …

During development of the vertebrate hindbrain, Hox genes play multiples roles in the
segmental processes that regulate anteroposterior (AP) patterning. Paralogous Hox genes …

During their differentiation epidermal cells of Drosophila form a rich variety of polarized
structures. These include the epidermal hairs that decorate much of the adult cuticular …

The Hoxb1 autoregulatory enhancer directs segmental expression in vertebrate hindbrain.
Three conserved repeats (R1, R2, and R3) in the enhancer have been described as Pbx …

The regulation of development by Hox proteins is important in the evolution of animal
morphology, but how the regulatory sequences of Hox-regulated target genes function and …

The basic-leucine zipper protein Cap 'n'collar B (CncB) suppresses the segmental identity
function of the Hox gene Deformed (Dfd) in the mandibular segment of Drosophila embryos …