Role of Neuropilin-2-mediated signaling axis in cancer progression and therapy resistance
Neuropilins (NRPs) are transmembrane proteins involved in vascular and nervous system
development by regulating angiogenesis and axon guidance cues. Several published …
development by regulating angiogenesis and axon guidance cues. Several published …
Stem cells as target for prostate cancer therapy: opportunities and challenges
C Escudero-Lourdes, I Alvarado-Morales… - Stem cell reviews and …, 2022 - Springer
Cancer stem cells (CSCs) and cells in a cancer stem cell-like (CSCL) state have proven to
be responsible for tumor initiation, growth, and relapse in Prostate Cancer (PCa) and other …
be responsible for tumor initiation, growth, and relapse in Prostate Cancer (PCa) and other …
Neuropilin-2 promotes lineage plasticity and progression to neuroendocrine prostate cancer
Neuroendocrine prostate cancer (NEPC), a lethal subset of prostate cancer, is characterized
by loss of AR signaling and resulting resistance to AR-targeted therapy during …
by loss of AR signaling and resulting resistance to AR-targeted therapy during …
Neuropilin 2 in osteoblasts regulates trabecular bone mass in male mice
L Verlinden, S Doms, I Janssens, MB Meyer… - Frontiers in …, 2023 - frontiersin.org
Introduction Neuropilin 2 (NRP2) mediates the effects of class 3 semaphorins and vascular
endothelial growth factor and is implicated in axonal guidance and angiogenesis. Moreover …
endothelial growth factor and is implicated in axonal guidance and angiogenesis. Moreover …
Orchestrating Resilience: How Neuropilin-2 and Macrophages Contribute to Cardiothoracic Disease
R Dhupar, AA Powers, SH Eisenberg… - Journal of Clinical …, 2024 - mdpi.com
Immunity has evolved to balance the destructive nature of inflammation with wound healing
to overcome trauma, infection, environmental insults, and rogue malignant cells. The …
to overcome trauma, infection, environmental insults, and rogue malignant cells. The …
Association of plasma NRP2 and VEGF‐C levels with prostate cancer disease severity
SA Mullen, D Das, N Ziamiavaghi, R High… - The …, 2024 - Wiley Online Library
Abstract Background Neuropilin 2 (NRP2) expression in tissue is an independent prognostic
factor for aggressive prostate cancer. Since the NRP2 pathway activation is thought to occur …
factor for aggressive prostate cancer. Since the NRP2 pathway activation is thought to occur …
Neuropilin2 in Mesenchymal Stromal Cells as a Potential Novel Therapeutic Target in Myelofibrosis
K Vosbeck, S Förster, T Mayr, A Sahu, EM Haddouti… - Cancers, 2024 - mdpi.com
Simple Summary Bone marrow (myelo-) fibrosis in myeloproliferative neoplasms is
associated with poor prognosis and treatment failure emphasizing the importance of …
associated with poor prognosis and treatment failure emphasizing the importance of …
NDRG1 过表达对去势抵抗性前列腺癌耐药细胞株C4-2/ENZA 耐药性的影响及其机制.
张鹰， 万朝辉， 蒋先训 - Journal of Jilin University (Medicine …, 2024 - search.ebscohost.com
目的: 探讨N-myc 下游调节基因1 (NDRG1) 对去势抵抗性前列腺癌(CRPC) 恩杂鲁胺(ENZA)
耐药的影响, 并阐明其作用机制. 方法: 体外培养人CRPC C4-2 细胞和ENZA 耐药株C4-2/ENZA …
耐药的影响, 并阐明其作用机制. 方法: 体外培养人CRPC C4-2 细胞和ENZA 耐药株C4-2/ENZA …
Identifizierung und Charakterisierung der regulatorischen Funktion von microRNAs innerhalb der NRP2/VEGFC-Achse im Harnblasenkarzinom
L Aldejohann-Bunk - 2023 - tud.qucosa.de
Abstract (DE) Als viert häufigste Karzinomerkrankung bei Männern und zwölft
häufigste bei Frauen in Deutschland ist das BCa weitverbreitet in der Gesellschaft. Dies …
häufigste bei Frauen in Deutschland ist das BCa weitverbreitet in der Gesellschaft. Dies …