Link between aluminum and the pathogenesis of Alzheimer′ s disease: the integration of the aluminum and amyloid cascade hypotheses

M Kawahara, M Kato-Negishi - International journal of …, 2011 - Wiley Online Library
Whilst being environmentally abundant, aluminum is not essential for life. On the contrary,
aluminum is a widely recognized neurotoxin that inhibits more than 200 biologically …

Multifaceted effects of aluminium in neurodegenerative diseases: A review

S Maya, T Prakash, KD Madhu, D Goli - Biomedicine & Pharmacotherapy, 2016 - Elsevier
Aluminium (Al) is the most common metal and widely distributed in our environment. Al was
first isolated as an element in 1827, and its use began only after 1886. Al is widely used for …

Neuromodulatory effect of curcumin on catecholamine systems and inflammatory cytokines in ovariectomized female rats

NM Saied, GS Georgy, RM Hussien… - Clinical and …, 2021 - Wiley Online Library
Anti‐inflammatory products may represent the future for depressive disorder therapies.
Curcumin (CUR) is a polyphenol and an active component of the turmeric plant Curcuma …

Neuroprotective effect of hesperidin on aluminium chloride induced Alzheimer's disease in Wistar rats

AJ Thenmozhi, TRW Raja, U Janakiraman… - Neurochemical …, 2015 - Springer
The present study was aimed to evaluate the protective effect of hesperidin (Hes) on
aluminium chloride (AlCl 3) induced neurobehavioral and pathological changes in …

Oxidative stress and mitochondrial dysfunction in aluminium neurotoxicity and its amelioration: a review

V Kumar, KD Gill - Neurotoxicology, 2014 - Elsevier
Aluminium is light weight and toxic metal present ubiquitously on earth which has gained
considerable attention due to its neurotoxic effects. The widespread use of products made …

Aluminium neurotoxicity: neurobehavioural and oxidative aspects

V Kumar, KD Gill - Archives of toxicology, 2009 - Springer
Aluminium is the most widely distributed metal in the environment and is extensively used in
daily life that provides easy exposure to human beings. The exposure to this toxic metal …

Acute aluminum chloride toxicity revisited: Study on DNA damage and histopathological, biochemical and neurochemical alterations in rat brain

L Liaquat, S Sadir, Z Batool, S Tabassum, S Shahzad… - Life sciences, 2019 - Elsevier
Aims Due to rapid increase in industrialization in the last few years, use of aluminum (Al)
and its alloys have been increased in different industrial fields. Ample evidence supports the …

Evaluating potential of curcumin loaded solid lipid nanoparticles in aluminium induced behavioural, biochemical and histopathological alterations in mice brain

V Kakkar, IP Kaur - Food and chemical toxicology, 2011 - Elsevier
Aluminium, a well established neurotoxicant, is reported to be involved in the aetiology of
Alzheimer's disease (AD) due to its easy admittance and accumulation in central nervous …

Efficacy of a natural coagulant protein from Moringa oleifera (Lam) seeds in treatment of Opa reservoir water, Ile-Ife, Nigeria

AS Taiwo, K Adenike, O Aderonke - Heliyon, 2020 - cell.com
Health related and environmental side effects associated with conventional chemical
coagulants used in water treatment has prompted the search for natural alternatives …

Metal ions influx is a double edged sword for the pathogenesis of Alzheimer's disease

P Wang, ZY Wang - Ageing Research Reviews, 2017 - Elsevier
Alzheimer's disease (AD) is a common form of dementia in aged people, which is defined by
two pathological characteristics: β-amyloid protein (Aβ) deposition and tau …