Developmental encephalopathies, including intellectual disability and autistic spectrum
disorder, are frequently associated with infant epilepsy. Epileptic encephalopathy is used to …

Epileptogenesis in infants with tuberous sclerosis complex (TSC) is a gradual and dynamic
process, leading to early onset and difficult-to-treat seizures. Several cellular, molecular and …

Epilepsy is a neurological disorder that poses a major threat to public health.
Hyperactivation of mTOR complex 1 (mTORC1) is believed to lead to abnormal network …

Autophagy is an explicit cellular process to deliver dissimilar cytoplasmic misfolded proteins,
lipids and damaged organelles to the lysosomes for degradation and elimination. The …

Recent advances in pharmacotherapy for epilepsy : Current Opinion in Neurology Recent
advances in pharmacotherapy for epilepsy : Current Opinion in Neurology Log in or Register …

Epilepsy is a chronic neurological disease characterized by recurrent seizures. Epilepsy is
observed as a well‐controlled disease by anti‐epileptic agents (AEAs) in about 69 …

Introduction Epilepsy is one of the most common and serious brain syndromes and has
adverse consequences on a patient's neurobiological, cognitive, psychological, and social …

Epilepsy affects approximately 1% of the world population. Patients have recurrent seizures,
increased physical and psychiatric comorbidities, and higher mortality rate than the general …

Hyperactivation of the mammalian target of rapamycin (mTOR) pathway can cause
malformation of cortical development (MCD) with associated epilepsy and intellectual …

Tuberous sclerosis complex (TSC) is a multisystem developmental disorder characterized
by hamartomas in various organs, such as the brain, lungs, and kidneys. Epilepsy, along …