Dysregulated growth hormone (GH) hypersecretion is usually caused by a GH-secreting
pituitary adenoma and leads to acromegaly—a disorder of disproportionate skeletal, tissue …

Prolactinomas account for approximately 40% of all pituitary adenomas and are an
important cause of hypogonadism and infertility. The ultimate goal of therapy for …

The WHO categorizes pituitary tumours as typical adenomas, atypical adenomas and
pituitary carcinomas, with typical adenomas constituting the major class. However, the WHO …

Pituitary adenomas are usually benign monoclonal tumours presenting either due to
hypersecretion of pituitary hormones, and/or due to local space occupying effects and …

The term" TSH-secreting pituitary tumors" includes two opposite clinical conditions: true
thyrotroph neoplasia that results in secondary hyperthyroidism, also called" central …

Pathogenesis of tumor formation in the anterior pituitary has been intensively studied, but
the common mechanism involved in pituitary cell transformation and tumorigenesis remains …

Pituitary tumours are common and show a range of hormonal and proliferative behaviours
that provide a model for the study of neoplasia mechanisms. Mutations in classic oncogenes …

PITUITARY tumors are common neoplasms that exhibit a wide range of biological behavior,
in terms of hormonal and proliferative activities. Their hormonal activity is usually reflective of …

Hyperprolactinemia is one of the most frequently diagnosed clinical disorders in routine
endocrine practice. Any process interfering with dopamine synthesis, its transport to the …

We recently cloned a novel pituitary tumor transforming gene (PTTG). Here we report PTTG
expression in human pituitary adenomas and in normal pituitary tissue. In situ hybridization …