The molecular basis of simple relationships between exposure concentration and toxic effects with time

HA Tennekes, F Sánchez-Bayo - Toxicology, 2013 - Elsevier
Understanding the toxicity of chemicals to organisms requires considering the molecular
mechanisms involved as well as the relationships between exposure concentration and …

Review of toxicological effects caused by episodic stressor exposure

AK Gordon, SK Mantel… - … Toxicology and Chemistry, 2012 - Wiley Online Library
Water quality monitoring tools that rely on data from stress‐response tests with continuous
exposure at constant concentrations are not always appropriately protective when stressor …

From simple toxicological models to prediction of toxic effects in time

F Sánchez-Bayo - Ecotoxicology, 2009 - Springer
The ability to predict the effects of toxicants in organisms with reasonable accuracy depends
to a great extent on the toxico-kinetic models used to describe such effects. Toxic effects of …

Physiologically based toxicokinetic (PBTK) modeling in ecotoxicology

K Krishnan, T Peyret - Ecotoxicology modeling, 2009 - Springer
Abstract Physiologically based toxicokinetic [(PBTK), or alternatively referred to as
physiologically based pharmacokinetic (PBPK)] models are quantitative descriptions of …

Effects of ZnO nanomaterials on Xenopus laevis growth and development

S Nations, M Long, M Wages, J Canas, JD Maul… - Ecotoxicology and …, 2011 - Elsevier
The objectives of this study were to quantify uptake and developmental effects of zinc oxide
nanomaterials (nano-ZnO) on Xenopus laevis throughout the metomormosis process. To …

Application of toxicokinetic–toxicodynamic models in the aquatic ecological risk assessment of metals: A review

Y Gao - Environmental Toxicology and Pharmacology, 2024 - Elsevier
The issue of toxic metal pollution is a considerable environmental concern owing to its
complex nature, spatial and temporal variability, and susceptibility to environmental factors …

Toxicity of Two Pulsed Metal Exposures to Daphnia magna: Relative Effects of Pulsed Duration-Concentration and Influence of Interpulse Period

TC Hoang, JS Gallagher, JR Tomasso… - Archives of Environmental …, 2007 - Springer
Aquatic organisms living in surface waters experience fluctuating contaminant exposures
that vary in concentration, duration, and frequency. This study characterized the role of …

Concentration-dependent effects of waterborne zinc on population dynamics of Gyrodactylus turnbulli (Monogenea) on isolated guppies (Poecilia reticulata)

C Gheorgiu, DJ Marcogliese, M Scott - Parasitology, 2006 - cambridge.org
The effect of waterborne zinc (Zn) on Gyrodactylus population dynamics was studied on
isolated guppies maintained at concentrations ranging from 0 to 240 μg Zn/l. After 1 week …

Earthworms and their use in eco (toxico) logical modeling

WJGM Peijnenburg, MG Vijver - Ecotoxicology modeling, 2009 - Springer
A healthy terrestrial food web is essential for the sustainable use of soils. Earthworms are
key species within terrestrial food webs and perform a number of essential functionalities …

An integrated model describing the toxic responses of Daphnia magna to pulsed exposures of three metals

TC Hoang, JR Tomasso… - … Toxicology and Chemistry …, 2007 - Wiley Online Library
Some toxicology research in which toxicant exposures are continual (pulsed) rather than
continuous have been reported. A number of toxicity models have been developed for …